[HTML][HTML] Gliding motility powers invasion and egress in Apicomplexa
K Frénal, JF Dubremetz, M Lebrun… - Nature Reviews …, 2017 - nature.com
Protozoan parasites have developed elaborate motility systems that facilitate infection and
dissemination. For example, amoebae use actin-rich membrane extensions called …
dissemination. For example, amoebae use actin-rich membrane extensions called …
Toxoplasma Effectors Targeting Host Signaling and Transcription
Early electron microscopy studies revealed the elaborate cellular features that define the
unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) …
unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) …
Origin and arrangement of actin filaments for gliding motility in apicomplexan parasites revealed by cryo-electron tomography
M Martinez, SK Mageswaran, A Guérin… - Nature …, 2023 - nature.com
The phylum Apicomplexa comprises important eukaryotic parasites that invade host tissues
and cells using a unique mechanism of gliding motility. Gliding is powered by actomyosin …
and cells using a unique mechanism of gliding motility. Gliding is powered by actomyosin …
The molecular basis of erythrocyte invasion by malaria parasites
Plasmodium species cause malaria by proliferating in human erythrocytes. Invasion of
immunologically privileged erythrocytes provides a relatively protective niche as well as …
immunologically privileged erythrocytes provides a relatively protective niche as well as …
Plasma Membrane Association by N-Acylation Governs PKG Function in Toxoplasma gondii
Cyclic GMP (cGMP)-dependent protein kinase (protein kinase G [PKG]) is essential for
microneme secretion, motility, invasion, and egress in apicomplexan parasites, However …
microneme secretion, motility, invasion, and egress in apicomplexan parasites, However …
Molecular characterization of the conoid complex in Toxoplasma reveals its conservation in all apicomplexans, including Plasmodium species
The apical complex is the instrument of invasion used by apicomplexan parasites, and the
conoid is a conspicuous feature of this apparatus found throughout this phylum. The conoid …
conoid is a conspicuous feature of this apparatus found throughout this phylum. The conoid …
How apicomplexa parasites secrete and build their invasion machinery
MM Cova, MH Lamarque… - Annual Review of …, 2022 - annualreviews.org
Apicomplexa are obligatory intracellular parasites that sense and actively invade host cells.
Invasion is a conserved process that relies on the timely and spatially controlled exocytosis …
Invasion is a conserved process that relies on the timely and spatially controlled exocytosis …
[HTML][HTML] Conoid extrusion regulates glideosome assembly to control motility and invasion in Apicomplexa
N Dos Santos Pacheco, L Brusini, R Haase… - Nature …, 2022 - nature.com
Members of Apicomplexa are defined by apical cytoskeletal structures and secretory
organelles, tailored for motility, invasion and egress. Gliding is powered by actomyosin …
organelles, tailored for motility, invasion and egress. Gliding is powered by actomyosin …
Biogenesis and discharge of the rhoptries: Key organelles for entry and hijack of host cells by the Apicomplexa
R Ben Chaabene, G Lentini… - Molecular …, 2021 - Wiley Online Library
Rhoptries are specialized secretory organelles found in the Apicomplexa phylum, playing a
central role in the establishment of parasitism. The rhoptry content includes membranous as …
central role in the establishment of parasitism. The rhoptry content includes membranous as …
Life cycle stages, specific organelles and invasion mechanisms of Eimeria species
A Burrell, FM Tomley, S Vaughan… - Parasitology, 2020 - cambridge.org
Apicomplexans, including species of Eimeria, pose a real threat to the health and wellbeing
of animals and humans. Eimeria parasites do not infect humans but cause an important …
of animals and humans. Eimeria parasites do not infect humans but cause an important …