Therapeutic drug monitoring of tacrolimus-personalized therapy: second consensus report
M Brunet, T Van Gelder, A Åsberg… - Therapeutic drug …, 2019 - journals.lww.com
Ten years ago, a consensus report on the optimization of tacrolimus was published in this
journal. In 2017, the Immunosuppressive Drugs Scientific Committee of the International …
journal. In 2017, the Immunosuppressive Drugs Scientific Committee of the International …
NFAT control of innate immunity
The calcineurin/nuclear factor of activated T cells (NFAT) signaling pathway mediates
multiple adaptive T-cell functions, but recent studies have shown that calcineurin/NFAT …
multiple adaptive T-cell functions, but recent studies have shown that calcineurin/NFAT …
Defective localization with impaired tumor cytotoxicity contributes to the immune escape of NK cells in pancreatic cancer patients
SA Lim, J Kim, S Jeon, MH Shin, J Kwon… - Frontiers in …, 2019 - frontiersin.org
Tumor-infiltrating lymphocytes (TILs), found in patients with advanced pancreatic ductal
adenocarcinoma (PDAC), are shown to correlate with overall survival (OS) rate. Although …
adenocarcinoma (PDAC), are shown to correlate with overall survival (OS) rate. Although …
Clinical relevance of natural killer cells following hematopoietic stem cell transplantation
JM Palmer, K Rajasekaran, MS Thakar… - Journal of …, 2012 - pmc.ncbi.nlm.nih.gov
Natural killer (NK) cells are one of the first cells to recover following allogeneic
hematopoietic stem cell transplantation (HSCT), and are believed to play an important role …
hematopoietic stem cell transplantation (HSCT), and are believed to play an important role …
Hypoxia-driven HIF-1α activation reprograms pre-activated NK cells towards highly potent effector phenotypes via ERK/STAT3 pathways
Simple Summary In patients with advanced cancer, hypoxic stress shapes NK cells toward
tumor-resistant and immunosuppressive phenotypes. Therefore, a strategy to restore NK cell …
tumor-resistant and immunosuppressive phenotypes. Therefore, a strategy to restore NK cell …
Small-Molecule Immunosuppressive Drugs and Therapeutic Immunoglobulins Differentially Inhibit NK Cell Effector Functions in vitro
A Pradier, M Papaserafeim, N Li, A Rietveld… - Frontiers in …, 2019 - frontiersin.org
Small-molecule immunosuppressive drugs (ISD) prevent graft rejection mainly by inhibiting
T lymphocytes. Therapeutic immunoglobulins (IVIg) are used for substitution, antibody …
T lymphocytes. Therapeutic immunoglobulins (IVIg) are used for substitution, antibody …
Ex Vivo Expansion of Highly Cytotoxic Human NK Cells by Cocultivation with Irradiated Tumor Cells for Adoptive Immunotherapy
Adoptive natural killer (NK) cell therapy may offer an effective treatment regimen for cancer
patients whose disease is refractory to conventional therapy. NK cells can kill a wide range …
patients whose disease is refractory to conventional therapy. NK cells can kill a wide range …
Co-infection of Cytomegalovirus and Epstein-Barr Virus Diminishes the Frequency of CD56dimNKG2A+KIR− NK Cells and Contributes to Suboptimal Control of …
Post-transplant lymphoproliferative disorder (PTLD) is a rare but potentially life-threatening
complication, frequently associated with Epstein-Barr virus (EBV), which develops after solid …
complication, frequently associated with Epstein-Barr virus (EBV), which develops after solid …
The peripheral NK cell repertoire after kidney transplantation is modulated by different immunosuppressive drugs
C Neudoerfl, BJ Mueller, C Blume, K Daemen… - Frontiers in …, 2013 - frontiersin.org
In the context of kidney transplantation, little is known about the involvement of natural killer
(NK) cells in the immune reaction leading to either rejection or immunological tolerance …
(NK) cells in the immune reaction leading to either rejection or immunological tolerance …
Examining the impact of immunosuppressive drugs on antibody-dependent cellular cytotoxicity (ADCC) of human peripheral blood natural killer (NK) cells and gamma …
S Jalali, S Stankovic, GP Westall, PC Reading… - Transplant …, 2024 - Elsevier
Background Human natural killer (NK) cells and gamma delta (γδ) T cells may impact
outcomes of solid organ transplantation (SOT) such as lung transplantation (LTx) following …
outcomes of solid organ transplantation (SOT) such as lung transplantation (LTx) following …