[HTML][HTML] Effects of endocrine disrupting chemicals on gonad development: Mechanistic insights from fish and mammals

G Delbes, M Blázquez, JI Fernandino, P Grigorova… - Environmental …, 2022 - Elsevier
Over the past century, evidence has emerged that endocrine disrupting chemicals (EDCs)
have an impact on reproductive health. An increased frequency of reproductive disorders …

[HTML][HTML] Molecular biological, physiological, cytological, and epigenetic mechanisms of environmental sex differentiation in teleosts: A systematic review

Y Yu, M Chen, ZG Shen - Ecotoxicology and Environmental Safety, 2023 - Elsevier
Human activities have been exerting widespread stress and environmental risks in aquatic
ecosystems. Environmental stress, including temperature rise, acidification, hypoxia, light …

Paternal methotrexate exposure affects sperm small RNA content and causes craniofacial defects in the offspring

N Alata Jimenez, M Castellano, EM Santillan… - Nature …, 2023 - nature.com
Folate is an essential vitamin for vertebrate embryo development. Methotrexate (MTX) is a
folate antagonist that is widely prescribed for autoimmune diseases, blood and solid organ …

Knock-out of vasotocin reduces reproductive success in female zebrafish, Danio rerio

D Ramachandran, K Sharma, V Saxena… - Frontiers in …, 2023 - frontiersin.org
The vertebrate nonapeptide vasotocin/vasopressin is evolutionarily highly conserved and
acts as neuromodulator and endocrine/paracrine signaling molecule. Circumstantial and …

Diazepam at environmentally relevant concentrations disturbed social interactions and brain neurotransmitters in adult Japanese medaka (Oryzias latipes)

X Qiu, S Wang, M Zhuo, Y Shi, K Chen - Aquatic Toxicology, 2023 - Elsevier
Pollution by diazepam (DZP) is increasingly recognized as a major threat to aquatic
organisms, but knowledge about its potential risk to fish is still limited. In this study, we …

Thyroid axis participates in high-temperature-induced male sex reversal through its activation by the stress response

DC Castañeda-Cortés, IF Rosa, AF Boan… - Cellular and Molecular …, 2023 - Springer
Environmental changes alter the sex fate in about 15% of vertebrate orders, mainly in
ectotherms such as fish and reptiles. However, the effects of temperature changes on the …

A83-01 and DMH1 effects in the zebrafish spermatogonial niche: Unraveling the roles of TGF-β and BMP signaling in the Fsh-mediated spermatogonial fate

DF da Costa, A de Oliveira Ribeiro, JMB Ricci… - Gene, 2024 - Elsevier
Transforming growth factor-β (TGF-β) and bone morphogenetic protein (BMP) signaling has
fundamental roles in the regulation of the stem cell niche for both embryonic and adult stem …

Reproductive roles of the vasopressin/oxytocin neuropeptide family in teleost fishes

JA Mennigen, D Ramachandran, K Shaw… - Frontiers in …, 2022 - frontiersin.org
The vertebrate nonapeptide families arginine vasopressin (AVP) and oxytocin (OXT) are
considered to have evolved from a single vasopressin-like peptide present in invertebrates …

Notch pathway is required for protection against heat stress in spermatogonial stem cells in medaka

OD Moreno Acosta, AF Boan, RS Hattori… - Fish Physiology and …, 2023 - Springer
Gamete production is a fundamental process for reproduction; however, exposure to stress,
such as increased environmental temperature, can decrease or even interrupt this process …

Atrazine alters early sexual development of the South American silverside, Odontesthes bonariensis

P Carriquiriborde, JI Fernandino, CG López… - Aquatic Toxicology, 2023 - Elsevier
Atrazine (ATZ) is a frequent contaminant in freshwater ecosystems within agricultural
regions. The capacity of this herbicide to interfere with the vertebrate endocrine system is …