Sex differences in Alzheimer disease—the gateway to precision medicine
Alzheimer disease (AD) is characterized by wide heterogeneity in cognitive and behavioural
syndromes, risk factors and pathophysiological mechanisms. Addressing this phenotypic …
syndromes, risk factors and pathophysiological mechanisms. Addressing this phenotypic …
Brain atrophy in Alzheimer's disease and aging
Thanks to its safety and accessibility, magnetic resonance imaging (MRI) is extensively used
in clinical routine and research field, largely contributing to our understanding of the …
in clinical routine and research field, largely contributing to our understanding of the …
[HTML][HTML] A computational atlas of the hippocampal formation using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation of in vivo MRI
JE Iglesias, JC Augustinack, K Nguyen, CM Player… - Neuroimage, 2015 - Elsevier
Automated analysis of MRI data of the subregions of the hippocampus requires
computational atlases built at a higher resolution than those that are typically used in current …
computational atlases built at a higher resolution than those that are typically used in current …
Automated volumetry and regional thickness analysis of hippocampal subfields and medial temporal cortical structures in mild cognitive impairment
We evaluate a fully automatic technique for labeling hippocampal subfields and cortical
subregions in the medial temporal lobe in in vivo 3 Tesla MRI. The method performs …
subregions in the medial temporal lobe in in vivo 3 Tesla MRI. The method performs …
Structural imaging of hippocampal subfields in healthy aging and Alzheimer's disease
Hippocampal atrophy, as evidenced using magnetic resonance imaging (MRI), is one of the
most validated, easily accessible and widely used biomarkers of Alzheimer's disease (AD) …
most validated, easily accessible and widely used biomarkers of Alzheimer's disease (AD) …
Sex differences in the association between AD biomarkers and cognitive decline
Women are disproportionately affected by Alzheimer's disease (AD) in terms of both disease
prevalence and severity. Previous autopsy work has suggested that, in the presence of AD …
prevalence and severity. Previous autopsy work has suggested that, in the presence of AD …
Quantitative comparison of 21 protocols for labeling hippocampal subfields and parahippocampal subregions in in vivo MRI: towards a harmonized segmentation …
PA Yushkevich, RSC Amaral, JC Augustinack… - Neuroimage, 2015 - Elsevier
Objective An increasing number of human in vivo magnetic resonance imaging (MRI)
studies have focused on examining the structure and function of the subfields of the …
studies have focused on examining the structure and function of the subfields of the …
Baseline MRI predictors of conversion from MCI to probable AD in the ADNI cohort
The Alzheimer's Disease Neuroimaging Initiative (ADNI) is a multi-center study assessing
neuroimaging in diagnosis and longitudinal monitoring. Amnestic Mild Cognitive Impairment …
neuroimaging in diagnosis and longitudinal monitoring. Amnestic Mild Cognitive Impairment …
A comparison of automated segmentation and manual tracing for quantifying hippocampal and amygdala volumes
Large databases of high-resolution structural MR images are being assembled to
quantitatively examine the relationships between brain anatomy, disease progression …
quantitatively examine the relationships between brain anatomy, disease progression …
Multidimensional classification of hippocampal shape features discriminates Alzheimer's disease and mild cognitive impairment from normal aging
We describe a new method to automatically discriminate between patients with Alzheimer's
disease (AD) or mild cognitive impairment (MCI) and elderly controls, based on …
disease (AD) or mild cognitive impairment (MCI) and elderly controls, based on …