The multifaceted role of curcumin in advanced nanocurcumin form in the treatment and management of chronic disorders

P Tagde, P Tagde, F Islam, S Tagde, M Shah… - Molecules, 2021 - mdpi.com
Curcumin is the primary polyphenol in turmeric's curcuminoid class. It has a wide range of
therapeutic applications, such as anti-inflammatory, antioxidant, antidiabetic …

Targeting ubiquitin specific proteases (USPs) in cancer immunotherapy: from basic research to preclinical application

H Gao, J Yin, C Ji, X Yu, J Xue, X Guan… - Journal of Experimental …, 2023 - Springer
Tumors have evolved in various mechanisms to evade the immune system, hindering the
antitumor immune response and facilitating tumor progression. Immunotherapy has become …

Circular RNA circPOLR2A promotes clear cell renal cell carcinoma progression by facilitating the UBE3C-induced ubiquitination of PEBP1 and, thereby, activating the …

Z Xu, S Chen, R Liu, H Chen, B Xu, W Xu, M Chen - Molecular Cancer, 2022 - Springer
Background Increasing evidence has demonstrated that circular RNAs (circRNAs) are
implicated in cancer progression. However, the aberrant expression and biological functions …

Therapeutic insights on ferroptosis in Parkinson's disease

K Thapa, H Khan, N Kanojia, TG Singh, A Kaur… - European journal of …, 2022 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder that alters either motor or non-
motor activities. Dopamine-based medications can help alleviate symptoms at an early …

Multiple health benefits of curcumin and its therapeutic potential

M Shah, W Murad, S Mubin, O Ullah… - … Science and Pollution …, 2022 - Springer
Turmeric, or Curcuma longa as it is formally named, is a multifunctional plant with numerous
names. It was dubbed “the golden spice” and “Indian saffron” not only for its magnificent …

Understanding mechanistic aspect of the therapeutic role of herbal agents on neuroplasticity in cerebral ischemic-reperfusion injury

A Bangar, H Khan, A Kaur, K Dua, TG Singh - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Stroke is one of the leading causes of death and disability.
The only FDA-approved therapy for treating stroke is tissue plasminogen activator (tPA) …

Caspase-mediated regulation of the distinct signaling pathways and mechanisms in neuronal survival

H Khan, A Bangar, AK Grewal, P Bansal… - International …, 2022 - Elsevier
Caspases are intimately associated with altering various signaling pathways, resulting in
programmed cell death or apoptosis. Apoptosis is necessary for the normal homeostasis of …

Mechanistic insight on autophagy modulated molecular pathways in cerebral ischemic injury: from preclinical to clinical perspective

P Kalra, H Khan, A Kaur, TG Singh - Neurochemical Research, 2022 - Springer
Cerebral ischemia is one of the most devastating brain injuries and a primary cause of
acquired and persistent disability worldwide. Despite ongoing therapeutic interventions at …

Targeting ferroptosis in ischemia/reperfusion renal injury

K Thapa, TG Singh, A Kaur - Naunyn-Schmiedeberg's Archives of …, 2022 - Springer
Renal I/R injury is a severe medical condition contributing to acute kidney injury (AKI),
leading to rapid kidney dysfunction and high mortality rates. It is generally observed during …

In silico, in vitro screening of antioxidant and anticancer potentials of bioactive secondary metabolites from an endophytic fungus (Curvularia sp.) from Phyllanthus …

AK Kalimuthu, P Parasuraman, P Sivakumar… - … Science and Pollution …, 2022 - Springer
The main objective of this research work is to discover novel and efficient phytochemical
substances from endophytic fungus found in medicinal plants. Curvularia geniculata L.(C …