Abstract The Nrf2/Keap1 pathway is an important signaling cascade responsible for the
resistance of oxidative damage induced by exogenous chemicals. It maintains the redox …

Arachidonic acid can be oxygenated by a variety of different enzymes, including
lipoxygenases, cyclooxygenases, and cytochrome P450s, and can be converted to a …

The antitumorigenic mechanism of cannabidiol is still controversial. This study investigates
the role of COX-2 and PPAR-γ in cannabidiol's proapoptotic and tumor-regressive action. In …

Peroxisome proliferator‐activated receptor gamma (PPARγ) is a vital subtype of the PPAR
family. The biological functions are complex and diverse. PPARγ plays a significant role in …

Most investigations of iodine metabolism in humans and animals have focused on its role in
thyroid function. However, considerable evidence indicates that iodine could also be …

Background: Seaweed is an important dietary component and a rich source of iodine in
several chemical forms in Asian communities. Their high consumption of this element (25 …

Background: Cancer is a major cause of mortality worldwide with increasing numbers by the
years. In North Africa, the number of cancer patients is alarming. Also shocking is that a …

Gastric cancer (GC) is a lethal malignancy and the second most common cause of cancer-
related deaths. Although treatment options such as chemotherapy, radiotherapy, and …

Resistance is the major cause of treatment failure and disease progression in non-small cell
lung cancer (NSCLC). There is evidence that hypoxia is a key microenvironmental stress …

Hypertension, which often exists as a comorbid condition in cancer patients, is considered
as a factor affecting cancer progression. The renin-angiotensin system (RAS) plays an …