Organ transplantation is a lifesaving option for patients with advanced diseases. Rejection is
regarded as one of the most severe risk factors post-transplantation. A molecule that …

In the last few months, the coronavirus disease 2019 (COVID-19) pandemic has affected
millions of people worldwide and has provoked an exceptional effort from the scientific …

Chronic inflammation is linked to various diseases, including cancer, diabetes mellitus,
obesity, and hypertension. The critical question—how is chronic inflammation linked to acute …

Human Leukocyte Antigen-G (HLA-G), a polymorphic non-classical HLA (HLA-Ib) with
immune-regulatory properties in cancers and infectious diseases, presents both membrane …

Background An accelerated course of hepatic fibrosis may occur in liver transplantation (LT)
patients despite normal or slightly abnormal liver blood tests. Aim To identify screening tools …

Although human leukocyte antigen (HLA) gene polymorphism has been investigated in
many populations around the world, the data on MHC class I chain-related (MIC) genes are …

In the field of transplantation, expression of HLA-G, a nonclassical HLA molecule with
immunosuppressive functions and limited gene polymorphism, is considered beneficial for …

The immune system recognizes and attacks non-self antigens, making up the cornerstone of
immunity activity against infection. However, during organ transplantation, the immune …

This thesis addresses two pivotal issues in lung transplant recipients (LTRs): the detection of
biomarkers for acute rejection (AR) and an investigation into the immunogenicity of the …

Non alcoholic fatty liver disease (NAFLD) is the most common metabolic disease in humans,
affecting the majority of individuals. In the current investigation, we aim to identify potential …