Glioblastoma is the most common primary brain tumor and has a dismal prognosis. The
development of central necrosis represents a tipping point in the evolution of these tumors …

Simple Summary Tissue factor is a protein that is important for the regulation of blood
coagulation. New research has highlighted the important roles of tissue factor in cancer. This …

Hemochorial placentation is characterized by the development of trophoblast cells
specialized to interact with the uterine vascular bed. We utilized trophoblast stem (TS) cell …

Microparticles (MPs) are formed from platelets (PMPs), endothelial cells (EMPs) and
monocytes (MMPs), and in acute myocardial infarction (MI), there is an increase of MPs in …

Recent studies show that endothelial cell protein C receptor (EPCR) interacts with diverse
ligands, in addition to its known ligands protein C and activated protein C (APC). We …

Individuals with a bicuspid aortic valve (BAV) are at significantly higher risk of developing
aortic complications than individuals with tricuspid aortic valves (TAV) and defective …

Monocytes and monocyte-derived microvesicles (MVs) are the main source of circulating
tissue factor (TF). Increased monocyte TF expression and increased circulating levels of …

Tissue factor (TF), the key activator of the blood coagulation cascade and of thrombus
formation, is also expressed by circulating human platelets. Despite the documented in …

Cancer-associated thrombosis remains a significant complication in the clinical
management of cancer and interactions of the hemostatic system with cancer biology …

Tissue factor (TF) signalling has been associated with alterations in Akt activity influencing
cellular survival and proliferation. TF is also shown to induce signalling through activation of …