Blastomycosis is caused by a thermally dimorphic fungus that thrives in moist acidic soil.
Blastomyces dermatitidis is the species responsible for most infections in North America and …

Infections of the central nervous system (CNS) are infrequently diagnosed in
immunocompetent patients, but they do occur in a significant proportion of patients with …

Quantitative whole-body autoradiography was used to assess the distribution and tissue
penetration of isavuconazole in rats following single and repeated oral-dose administration …

Theranostic imaging methods could greatly enhance our understanding of the distribution of
CNS-acting drugs in individual patients. Fluorine-19 magnetic resonance imaging (19 F …

Objectives Voriconazole is a classical antifungal drug that is often used to treat CNS fungal
infections due to its permeability through the BBB. However, its clinical use remains …

Fluorinated ligands have a variety of uses in chemistry and industry, but it is their medical
applications as 18F‐labelled positron emission tomography (PET) tracers where they are …

Introduction: Brain abscess is an uncommon and potentially life-threatening infection of the
CNS that can be caused by a range of different pathogens including bacteria, fungi, and …

Over the past decade, fluorine (19F) magnetic resonance imaging (MRI) has garnered
significant scientific interest in the biomedical research community owing to the unique …

Objective We aimed to study the literature on chronic granulomatous invasive fungal
sinusitis to elucidate the changing trends in the management of the disease. Data Sources …

Antifungal agents can have complex dosing and the potential for drug interaction, both of
which can lead to subtherapeutic antifungal drug concentrations and poorer clinical …