Microbial production of advanced biofuels
Concerns over climate change have necessitated a rethinking of our transportation
infrastructure. One possible alternative to carbon-polluting fossil fuels is biofuels produced …
infrastructure. One possible alternative to carbon-polluting fossil fuels is biofuels produced …
Membrane active antimicrobial peptides: translating mechanistic insights to design
J Li, JJ Koh, S Liu, R Lakshminarayanan… - Frontiers in …, 2017 - frontiersin.org
Antimicrobial peptides (AMPs) are promising next generation antibiotics that hold great
potential for combating bacterial resistance. AMPs can be both bacteriostatic and …
potential for combating bacterial resistance. AMPs can be both bacteriostatic and …
A dual-mechanism antibiotic kills gram-negative bacteria and avoids drug resistance
JK Martin, JP Sheehan, BP Bratton, GM Moore… - Cell, 2020 - cell.com
The rise of antibiotic resistance and declining discovery of new antibiotics has created a
global health crisis. Of particular concern, no new antibiotic classes have been approved for …
global health crisis. Of particular concern, no new antibiotic classes have been approved for …
Antimicrobial peptides: challenging journey to the pharmaceutical, biomedical, and cosmeceutical use
A Mazurkiewicz-Pisarek, J Baran, T Ciach - International journal of …, 2023 - mdpi.com
Antimicrobial peptides (AMPs), or host defence peptides, are short proteins in various life
forms. Here we discuss AMPs, which may become a promising substitute or adjuvant in …
forms. Here we discuss AMPs, which may become a promising substitute or adjuvant in …
Mechanisms of envelope permeability and antibiotic influx and efflux in Gram-negative bacteria
Researchers, clinicians and governments all recognize antimicrobial resistance as a serious
and growing threat worldwide. New antimicrobials are urgently needed, especially for …
and growing threat worldwide. New antimicrobials are urgently needed, especially for …
Outer membrane permeability and antibiotic resistance
AH Delcour - Biochimica et Biophysica Acta (BBA)-Proteins and …, 2009 - Elsevier
To date most antibiotics are targeted at intracellular processes, and must be able to
penetrate the bacterial cell envelope. In particular, the outer membrane of gram-negative …
penetrate the bacterial cell envelope. In particular, the outer membrane of gram-negative …
Assembly and maintenance of lipids at the bacterial outer membrane
E Lundstedt, D Kahne, N Ruiz - Chemical reviews, 2020 - ACS Publications
The outer membrane of Gram-negative bacteria is essential for their survival in harsh
environments and provides intrinsic resistance to many antibiotics. This membrane is …
environments and provides intrinsic resistance to many antibiotics. This membrane is …
Metformin restores tetracyclines susceptibility against multidrug resistant bacteria
Highly persistent incidence of multidrug resistant (MDR) bacterial pathogens constitutes a
global burden for public health. An alternative strategy to alleviate such a crisis is to identify …
global burden for public health. An alternative strategy to alleviate such a crisis is to identify …
Type V secretion systems: an overview of passenger domain functions
I Meuskens, A Saragliadis, JC Leo… - Frontiers in microbiology, 2019 - frontiersin.org
Bacteria secrete proteins for different purposes such as communication, virulence functions,
adhesion to surfaces, nutrient acquisition, or growth inhibition of competing bacteria. For …
adhesion to surfaces, nutrient acquisition, or growth inhibition of competing bacteria. For …
Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria
β-Barrel outer membrane proteins (OMPs) represent the major proteinaceous component of
the outer membrane (OM) of Gram-negative bacteria. These proteins perform key roles in …
the outer membrane (OM) of Gram-negative bacteria. These proteins perform key roles in …