Print me an organ! Why we are not there yet

WL Ng, CK Chua, YF Shen - Progress in Polymer Science, 2019 - Elsevier
Bioprinting offers a highly-automated and advanced manufacturing platform that facilitates
the deposition of bio-inks (living cells, biomaterials and growth factors) in a scalable and …

Advancing biomaterials of human origin for tissue engineering

FM Chen, X Liu - Progress in polymer science, 2016 - Elsevier
Biomaterials have played an increasingly prominent role in the success of biomedical
devices and in the development of tissue engineering, which seeks to unlock the …

3D printing of scaffolds for tissue regeneration applications

AV Do, B Khorsand, SM Geary… - Advanced healthcare …, 2015 - Wiley Online Library
The current need for organ and tissue replacement, repair, and regeneration for patients is
continually growing such that supply is not meeting demand primarily due to a paucity of …

Digitally tunable microfluidic bioprinting of multilayered cannular tissues

Q Pi, S Maharjan, X Yan, X Liu, B Singh… - Advanced …, 2018 - Wiley Online Library
Despite advances in the bioprinting technology, biofabrication of circumferentially
multilayered tubular tissues or organs with cellular heterogeneity, such as blood vessels …

Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform

A Skardal, SV Murphy, M Devarasetty, I Mead… - Scientific reports, 2017 - nature.com
Many drugs have progressed through preclinical and clinical trials and have been available–
for years in some cases–before being recalled by the FDA for unanticipated toxicity in …

Direct-write bioprinting of cell-laden methacrylated gelatin hydrogels

LE Bertassoni, JC Cardoso, V Manoharan… - …, 2014 - iopscience.iop.org
Fabrication of three dimensional (3D) organoids with controlled microarchitectures has been
shown to enhance tissue functionality. Bioprinting can be used to precisely position cells …

Tissue engineering: toward a new era of medicine

A Shafiee, A Atala - Annual review of medicine, 2017 - annualreviews.org
The goal of tissue engineering is to mitigate the critical shortage of donor organs via in vitro
fabrication of functional biological structures. Tissue engineering is one of the most …

Engineering complex tissues

A Atala, FK Kasper, AG Mikos - Science translational medicine, 2012 - science.org
Tissue engineering has emerged at the intersection of numerous disciplines to meet a
global clinical need for technologies to promote the regeneration of functional living tissues …

A 3D bioprinting system to produce human-scale tissue constructs with structural integrity

HW Kang, SJ Lee, IK Ko, C Kengla, JJ Yoo… - Nature …, 2016 - nature.com
A challenge for tissue engineering is producing three-dimensional (3D), vascularized
cellular constructs of clinically relevant size, shape and structural integrity. We present an …

3D bioprinting of urethra with PCL/PLCL blend and dual autologous cells in fibrin hydrogel: An in vitro evaluation of biomimetic mechanical property and cell growth …

K Zhang, Q Fu, J Yoo, X Chen, P Chandra, X Mo… - Acta biomaterialia, 2017 - Elsevier
Objective Urethral stricture is a common condition seen after urethral injury. The currently
available treatments are inadequate and there is a scarcity of substitute materials used for …