Structural and functional consequences of reversible lipid asymmetry in living membranes

M Doktorova, JL Symons, I Levental - Nature chemical biology, 2020 - nature.com
Maintenance of lipid asymmetry across the two leaflets of the plasma membrane (PM)
bilayer is a ubiquitous feature of eukaryotic cells. Loss of this asymmetry has been widely …

Membrane lipid nanodomains

M Cebecauer, M Amaro, P Jurkiewicz… - Chemical …, 2018 - ACS Publications
Lipid membranes can spontaneously organize their components into domains of different
sizes and properties. The organization of membrane lipids into nanodomains might …

Asymmetric lipid membranes: towards more realistic model systems

D Marquardt, B Geier, G Pabst - Membranes, 2015 - mdpi.com
Despite the ubiquity of transbilayer asymmetry in natural cell membranes, the vast majority
of existing research has utilized chemically well-defined symmetric liposomes, where the …

Nonuniversal impact of cholesterol on membranes mobility, curvature sensing and elasticity

M Pöhnl, MFW Trollmann, RA Böckmann - Nature Communications, 2023 - nature.com
Biological membranes, composed mainly of phospholipids and cholesterol, play a vital role
as cellular barriers. They undergo localized reshaping in response to environmental cues …

Mitochondrial cristae architecture and functions: lessons from minimal model systems

F Joubert, N Puff - Membranes, 2021 - mdpi.com
Mitochondria are known as the powerhouse of eukaryotic cells. Energy production occurs in
specific dynamic membrane invaginations in the inner mitochondrial membrane called …

Pore formation in lipid membrane I: Continuous reversible trajectory from intact bilayer through hydrophobic defect to transversal pore

SA Akimov, PE Volynsky, TR Galimzyanov, PI Kuzmin… - Scientific reports, 2017 - nature.com
Lipid membranes serve as effective barriers allowing cells to maintain internal composition
differing from that of extracellular medium. Membrane permeation, both natural and artificial …

Probing elastic and viscous properties of phospholipid bilayers using neutron spin echo spectroscopy

M Nagao, EG Kelley, R Ashkar… - The journal of …, 2017 - ACS Publications
The elastic and viscous properties of self-assembled amphiphilic membranes dictate the
intricate hierarchy of their structure and dynamics ranging from the diffusion of individual …

[HTML][HTML] Direct and indirect cholesterol effects on membrane proteins with special focus on potassium channels

F Zakany, T Kovacs, G Panyi, Z Varga - … BBA)-Molecular and Cell Biology of …, 2020 - Elsevier
As described in the literature the interaction between cholesterol and membrane proteins
can occur via direct, ligand-like and indirect mechanisms, in which cholesterol effects are …

Cyclodextrins: Only pharmaceutical excipients or full-fledged drug candidates?

T Kovacs, P Nagy, G Panyi, L Szente, Z Varga… - Pharmaceutics, 2022 - mdpi.com
Cyclodextrins, representing a versatile family of cyclic oligosaccharides, have extensive
pharmaceutical applications due to their unique truncated cone-shaped structure with a …

[HTML][HTML] Physical mechanisms of micro-and nanodomain formation in multicomponent lipid membranes

F Schmid - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2017 - Elsevier
This article summarizes a variety of physical mechanisms proposed in the literature, which
can generate micro-and nanodomains in multicomponent lipid bilayers and biomembranes …