Recent progress in Lyme disease and remaining challenges

JR Bobe, BL Jutras, EJ Horn, ME Embers… - Frontiers in …, 2021 - frontiersin.org
Lyme disease (also known as Lyme borreliosis) is the most common vector-borne disease in
the United States with an estimated 476,000 cases per year. While historically, the long-term …

[PDF][PDF] Persistent symptoms after treatment of Lyme disease

A Marques - Infectious disease clinics of North America, 2022 - Elsevier
The controversy regarding the underlying mechanisms of PTLDs and the increasingly bitter
debate over CLD, continues unabated over the past years. If anything, it has become more …

A diagnostic classifier for gene expression-based identification of early Lyme disease

V Servellita, J Bouquet, A Rebman, T Yang… - Communications …, 2022 - nature.com
Background Lyme disease is a tick-borne illness that causes an estimated 476,000
infections annually in the United States. New diagnostic tests are urgently needed, as …

Biomarker selection and a prospective metabolite-based machine learning diagnostic for lyme disease

ER Kehoe, BL Fitzgerald, B Graham, MN Islam… - Scientific Reports, 2022 - nature.com
We provide a pipeline for data preprocessing, biomarker selection, and classification of
liquid chromatography–mass spectrometry (LCMS) serum samples to generate a …

Gene set predictor for post-treatment Lyme disease

DJB Clarke, AW Rebman, J Fan, MJ Soloski… - Cell Reports …, 2022 - cell.com
Lyme disease (LD) is tick-borne disease whose post-treatment sequelae are not well
understood. For this study, we enrolled 152 individuals with symptoms of post-treatment LD …

Physics-informed neural entangled-ladder network for inhalation impedance of the respiratory system

AK Kumar, S Jain, S Jain, M Ritam, Y Xia… - Computer Methods and …, 2023 - Elsevier
Abstract Background and Objectives: The use of machine learning methods for modelling
bio-systems is becoming prominent which can further improve bio-medical technologies …

The troublesome ticks research protocol: developing a comprehensive, multidiscipline research plan for investigating human tick-associated disease in Australia

AD Barbosa, M Long, W Lee, JM Austen, M Cunneen… - Pathogens, 2022 - mdpi.com
In Australia, there is a paucity of data about the extent and impact of zoonotic tick-related
illnesses. Even less is understood about a multifaceted illness referred to as Debilitating …

Protocol for a longitudinal cohort study of Lyme disease with physical, mental and immunological assessment

M Loeb, R Brison, J Bramson, T Hatchette, B Sander… - BMJ open, 2023 - bmjopen.bmj.com
Introduction There are limited data on the longitudinal impact of Lyme disease. Predictors of
recovery have not been fully established using validated data collection instruments. There …

Decoding SARS-CoV-2 Variants: An in-silico approach to RNA-Seq feature extraction using K-mers and N-grams

N Iqbal, A Bhardwaj - 2024 IEEE International Students' …, 2024 - ieeexplore.ieee.org
The world's enormous challenge is to combat the COVID-19 pandemic, which has spread by
the SARS-CoV-2 virus over the past three years. Many waves are formed with diverse …

[HTML][HTML] Cytokine Hub Classification of PASC, ME-CFS and other PASC-like Conditions

BK Patterson, J Guevara-Coto, EB Francisco… - 2022 - europepmc.org
Background: Post-acute sequelae of COVID-19 (PASC) is a growing healthcare and
economic concern affecting as many as 10%-30% of those infected with COVID-19. Though …