[HTML][HTML] The role of microtubules in the immune system and as potential targets for gut-based immunotherapy

T Ilan-Ber, Y Ilan - Molecular immunology, 2019 - Elsevier
Microtubules (MTs) are tubular polymers of tubulin that are highly dynamic and found
throughout the cytoplasm. MTs are involved in maintaining cell structure and, together with …

Mesenchymal stem cells tune the development of monocyte-derived dendritic cells toward a myeloid-derived suppressive phenotype through growth-regulated …

HW Chen, HY Chen, LT Wang, FH Wang… - The Journal of …, 2013 - journals.aai.org
Mesenchymal stem/stromal cells (MSCs) are promising potential candidates for the
treatment of immunological diseases because of their immunosuppressive functions …

[HTML][HTML] Humoral and cellular immunity in three different types of COVID-19 vaccines against SARS-CoV-2 variants in a real-world data analysis

YC Song, SJ Liu, HJ Lee, HC Liao, CT Liu… - Journal of Microbiology …, 2023 - Elsevier
Background An effective vaccine response is currently a critical issue in the control of COVID-
19. Little is known about humoral and cellular immunity comparing protein-based vaccine …

A potential herbal adjuvant combined with a peptide-based vaccine acts against HPV-related tumors through enhancing effector and memory T-cell immune …

YC Song, HC Huang, CYY Chang, HJ Lee… - Frontiers in …, 2020 - frontiersin.org
Viral infection is associated with many types of tumorigenesis, including human
papillomavirus (HPV)-induced cervical cancer. The induction of a specific T-cell response …

Self-adjuvanting lipoimmunogens for therapeutic HPV vaccine development: potential clinical impact

KY Shen, LS Chang, CH Leng, SJ Liu - Expert Review of Vaccines, 2015 - Taylor & Francis
The goal of therapeutic HPV vaccines is the induction of cytotoxic T lymphocyte immunity
against HPV-associated cancers. Recombinant proteins and synthetic peptides have high …

A TLR9 agonist enhances the anti-tumor immunity of peptide and lipopeptide vaccines via different mechanisms

YC Song, SJ Liu - Scientific reports, 2015 - nature.com
The toll-like receptor 9 (TLR9) agonists CpG oligodeoxynucleotides (CpG ODNs) have been
recognized as promising adjuvants for vaccines against infectious diseases and cancer …

[HTML][HTML] Disintegration and cancer immunotherapy efficacy of a squalane-in-water delivery system emulsified by bioresorbable poly (ethylene glycol)-block-polylactide

WL Chen, SJ Liu, CH Leng, HW Chen, P Chong… - Biomaterials, 2014 - Elsevier
Vaccine adjuvant is conferred on the substance that helps to enhance antigen-specific
immune response. Here we investigated the disintegration characteristics and …

Depletion of tumor-associated macrophages enhances the anti-tumor immunity induced by a Toll-like receptor agonist-conjugated peptide

KY Shen, YC Song, IH Chen, P Chong… - Human Vaccines & …, 2014 - Taylor & Francis
It has been reported that lipopeptides can be used to elicit cytotoxic T lymphocyte (CTL)
responses against viral diseases and cancer. In our previous study, we determined that …

Degradable emulsion as vaccine adjuvant reshapes antigen-specific immunity and thereby ameliorates vaccine efficacy

CH Huang, CY Huang, CP Cheng, SH Dai… - Scientific Reports, 2016 - nature.com
This study describes the feasibility and adjuvant mechanism of a degradable emulsion for
tuning adaptive immune responses to a vaccine antigen. We featured a mouse model with …

Thermal properties and physicochemical behavior in aqueous solution of pyrene-labeled poly (ethylene glycol)-polylactide conjugate

WL Chen, YF Peng, SK Chiang… - International Journal of …, 2015 - Taylor & Francis
A fluorescence-labeled bioresorbable polymer was prepared by a coupling reaction of poly
(ethylene glycol)-polylactide (PEG-PLA) with carboxyl pyrene, using N, N' …