[HTML][HTML] Antibody stability: A key to performance-Analysis, influences and improvement

H Ma, C Ó'Fágáin, R O'Kennedy - Biochimie, 2020 - Elsevier
An antibody's stability greatly influences its performance (ie its specificity and affinity). Thus,
stability is a major issue for researchers and manufacturers, especially with the increasing …

[HTML][HTML] Conditioned medium-electrospun fiber biomaterials for skin regeneration

L Chen, L Cheng, Z Wang, J Zhang, X Mao, Z Liu… - Bioactive Materials, 2021 - Elsevier
Conditioned medium (CM) contains variety of factors secreted by cells, which directly
regulate cellular processes, showing tremendous potential in regenerative medicine. Here …

Human fetal mesenchymal stem cells secretome promotes scarless diabetic wound healing through heat‐shock protein family

B Wang, M Pang, Y Song, H Wang, P Qi… - Bioengineering & …, 2023 - Wiley Online Library
The high mortality rate of patients with diabetic foot ulcers is urging the appearance of an
effective biomedical drug. Senescence is one of the major reasons of aging‐induced decline …

[HTML][HTML] The immunomodulatory activity of Chenopodium ambrosioides reduces the parasite burden and hepatic granulomatous inflammation in Schistosoma …

JGM Rodrigues, PSV Albuquerque… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Folk medicine reports have described the use of
Chenopodium ambrosioides as an anti-inflammatory, analgesic, and anthelmintic herb …

Direct cytosolic delivery of proteins using lyophilized and reconstituted polymer-protein assemblies

DC Luther, H Nagaraj, R Goswami, YA Çiçek… - Pharmaceutical …, 2022 - Springer
Purpose Cytosolic delivery of proteins accesses intracellular targets for chemotherapy and
immunomodulation. Current delivery systems utilize inefficient endosomal pathways of …

Immobilization of microbial multienzyme preparation on calcium alginate beads as well as lyophilization with mosambi peel matrix improved its shelf-life and stability

B Singh, SK Soni, S Vaish, P Mathur, N Garg - Folia Microbiologica, 2024 - Springer
The purpose of the current study was to evaluate the functional activity and storage viability
(at 4° C and 35° C) of an immobilized as well as lyophilized multienzyme, viz., pectinase …

[HTML][HTML] Primary Progenitor Tenocytes: Cytotherapeutics and Cell-Free Derivatives

A Laurent, C Scaletta, P Abdel-Sayed, W Raffoul… - Encyclopedia, 2023 - mdpi.com
Definition Primary progenitor tenocytes are diploid cells that may be cultured in vitro and
therapeutically used for allogeneic musculoskeletal regenerative medicine. Firstly, technical …

Established and Novel Excipients for Freeze-Drying of Proteins

I Seifert, W Friess - Freeze Drying of Pharmaceutical Products, 2019 - taylorfrancis.com
Stabilising excipients are essential in formulations of protein drug lyophilisates. Sugars such
as sucrose and trehalose are classically used as amorphous matrix formers, embedding the …

Rapid Detection of Serum Procalcitonin by Immunochromatograghy Technology Based on Freeze‐dried Up‐conversion Nanoparticles/Antibody Conjugates

L Lei, Y Zhou, Y Han, H Zhang - Chinese Journal of Chemistry, 2017 - Wiley Online Library
Procalcitonin (PCT) is a sensitive and specific biomarker for sepsis diagnosis and widely
used as a biomarker to improve the diagnosis of bacterial infections and to guide the …

Intracellular Delivery of Therapeutic Biomolecules through Versatile Polymer Nanotechnology

DC Luther - 2022 - scholarworks.umass.edu
Advancing pharmaceutical technology has made it possible to treat diseases once
considered 'undruggable.'Access to these new pharmaceutical targets is possible thanks to …