Mechanisms of diabetic foot ulceration: A review

H Deng, B Li, Q Shen, C Zhang, L Kuang… - Journal of …, 2023 - Wiley Online Library
Diabetic foot ulcers (DFUs) are associated with complex pathogenic factors and are
considered a serious complication of diabetes. The potential mechanisms underlying DFUs …

[HTML][HTML] LncRNAs associated with oxidative stress in diabetic wound healing: regulatory mechanisms and application prospects

Q Yang, D Fang, J Chen, S Hu, J Jiang, M Zeng… - Theranostics, 2023 - ncbi.nlm.nih.gov
Diabetes is a group of chronic diseases with blood glucose imbalance, and long-term
hyperglycaemia causes sustained damage to various organs of the body, resulting in …

Besides pathology: long non-coding RNA in cell and tissue homeostasis

A Salviano-Silva, SC Lobo-Alves, RC Almeida… - Non-coding RNA, 2018 - mdpi.com
A significant proportion of mammalian genomes corresponds to genes that transcribe long
non-coding RNAs (lncRNAs). Throughout the last decade, the number of studies concerning …

The role of Wnt signaling in skin fibrosis

MF Griffin, J Huber, FJ Evan, N Quarto… - Medicinal research …, 2022 - Wiley Online Library
Skin fibrosis is the excessive deposition of extracellular matrix in the dermis. Cutaneous
fibrosis can occur following tissue injury, including burns, trauma, and surgery, resulting in …

Regulatory mechanisms of the Wnt/β-catenin pathway in diabetic cutaneous ulcers

H Zhang, X Nie, X Shi, J Zhao, Y Chen, Q Yao… - Frontiers in …, 2018 - frontiersin.org
Skin ulcers are a serious complication of diabetes. Diabetic patients suffer from vascular
lesions and complications such as peripheral neuritis, peripheral vascular lesions, and …

Positive feedback loops between fibroblasts and the mechanical environment contribute to dermal fibrosis

L Zhu, L Liu, A Wang, J Liu, X Huang, T Zan - Matrix Biology, 2023 - Elsevier
Dermal fibrosis is characterized by excessive deposition of extracellular matrix in the dermis
and affects millions of people worldwide and causes limited movement, disfigurement and …

Transcriptional kinetics and molecular functions of long noncoding RNAs

P Johnsson, C Ziegenhain, L Hartmanis, GJ Hendriks… - Nature Genetics, 2022 - nature.com
An increasing number of long noncoding RNAs (lncRNAs) have experimentally confirmed
functions, yet little is known about their transcriptional dynamics and it is challenging to …

seRNA PAM controls skeletal muscle satellite cell proliferation and aging through trans regulation of Timp2 expression synergistically with Ddx5

KKH So, Y Huang, S Zhang, Y Qiao, L He, Y Li… - Aging cell, 2022 - Wiley Online Library
Muscle satellite cells (SCs) are responsible for muscle homeostasis and regeneration and
lncRNAs play important roles in regulating SC activities. Here, in this study, we identify PAM …

LncRNA XIST promotes extracellular matrix synthesis, proliferation and migration by targeting miR-29b-3p/COL1A1 in human skin fibroblasts after thermal injury

W Cao, Y Feng - Biological research, 2019 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) have been reported to be
associated with dermis process during burn wound healing. This study aimed to investigate …

Efficacy of probiotic Streptococcus thermophilus in counteracting TGF-β1-induced fibrotic response in normal human dermal fibroblasts

F Lombardi, FR Augello, S Artone, B Bahiti… - Journal of …, 2022 - Springer
Background Abnormal and deregulated skin wound healing associated with prolonged
inflammation may result in dermal fibrosis. Since the current therapeutic strategies revealed …