Mechanisms of dietary sodium-induced impairments in endothelial function and potential countermeasures

JC Patik, SL Lennon, WB Farquhar, DG Edwards - Nutrients, 2021 - mdpi.com
Despite decades of efforts to reduce sodium intake, excess dietary sodium remains
commonplace, and contributes to increased cardiovascular morbidity and mortality …

Nrf2-mediated dichotomy in the vascular system: Mechanistic and therapeutic perspective

W Wu, A Hendrix, S Nair, T Cui - Cells, 2022 - mdpi.com
Nuclear factor-erythroid 2-related factor 2 (Nrf2), a transcription factor, controls the
expression of more than 1000 genes that can be clustered into different categories with …

Total Glycosides of Cistanche deserticola Promote Neurological Function Recovery by Inducing Neurovascular Regeneration via Nrf-2/Keap-1 Pathway in MCAO/R …

F Wang, R Li, P Tu, J Chen, K Zeng… - Frontiers in …, 2020 - frontiersin.org
Background The traditional Chinese medicine Cistanche deserticola has been reported to
be valid for cardiovascular and cerebrovascular diseases. However, its active components …

The mitochondrial-derived peptide MOTS-c attenuates oxidative stress injury and the inflammatory response of H9c2 cells through the Nrf2/ARE and NF-κB pathways

C Shen, J Wang, M Feng, J Peng, X Du, H Chu… - Cardiovascular …, 2022 - Springer
Aim Oxidative stress and the inflammatory response contribute to the progression of
cardiovascular disease. The present study aimed to investigate whether the mitochondrial …

Novel strategies for healthy brain aging

D Wahl, AN Cavalier, TJ LaRocca - Exercise and sport sciences …, 2021 - journals.lww.com
One of the best strategies for healthy brain aging is regular aerobic exercise. Commonly
studied “anti-aging” compounds may mimic some effects of exercise on the brain, but novel …

Static stretching reduces motoneuron excitability: the potential role of neuromodulation

GS Trajano, AJ Blazevich - Exercise and sport sciences reviews, 2021 - journals.lww.com
Prolonged static muscle stretching transiently reduces maximal muscle force, and this force
loss has a strong neural component. In this review, we discuss the evidence suggesting that …

Hepatocellular carcinoma cell-derived extracellular vesicles encapsulated microRNA-584-5p facilitates angiogenesis through PCK1-mediated nuclear factor E2 …

Z Shao, Q Pan, Y Zhang - The International Journal of Biochemistry & Cell …, 2020 - Elsevier
Hepatocellular carcinoma (HCC) is a fatal disease characterized by poor liver function with
increasing morbidity and poor prognosis. Extracellular vesicles, released by different cells …

Costunolide covalently targets and inhibits CaMKII phosphorylation to reduce ischemia-associated brain damage

W Liu, W Yang, R Niu, L Cong, M Jiang, G Bai - Phytomedicine, 2023 - Elsevier
Background Chronic cerebral hypoperfusion (CCH) is a leading cause of disability and
mortality worldwide. Restoring cerebral blood flow (CBF) through vasodilatation is …

Nrf2-Keap1 in Cardiovascular Disease: Which is the Cart and Which the Horse?

N Dhyani, C Tian, L Gao, TL Rudebush… - Physiology, 2024 - journals.physiology.org
High levels of oxidant stress in the form of reactive oxidant species are prevalent in the
circulation and tissues in various types of cardiovascular disease including heart failure …

PROCJENA MOŽDANE VAZOREAKTIVNOSTI TRANSKRANIJSKIM DOPLEROM KOD BOLESNIKA S KRONIČNOM OPSTRUKTIVNOM PLUĆNOM BOLESTI

M Hlavati - 2020 - repozitorij.unios.hr
Sažetak Cilj istraživanja: Odrediti moždanu vazoreaktivnost u prednjoj i stražnjoj moždanoj
cirkulaciji pomoću metode voljnog zadržavanja daha kod bolesnika s kroničnom …