Recent approaches in the organocatalytic synthesis of pyrroles

B Borah, KD Dwivedi, LR Chowhan - RSC advances, 2021 - pubs.rsc.org
Organocatalysis has emerged as one of the most important tools for the synthesis of diverse
structural scaffolds, and has become one of the most important hot topics of current …

Phosphine‐catalyzed enantioselective dearomative [3+ 2]‐cycloaddition of 3‐nitroindoles and 2‐nitrobenzofurans

H Wang, J Zhang, Y Tu, J Zhang - Angewandte Chemie, 2019 - Wiley Online Library
Over the past years, the metal‐catalyzed dearomative cycloaddition of 3‐nitroindoles and 2‐
nitrobenzofurans have emerged as a powerful protocol to construct chiral fused heterocyclic …

Recent advances in the synthesis of imidazolines (2009–2020)

MSA Mehedi, JJ Tepe - Advanced Synthesis & Catalysis, 2020 - Wiley Online Library
Imidazoline is an important class of compounds found in numerous natural and
pharmaceutical products. The compounds are also used as an intermediate in the synthesis …

Silver-Catalyzed Asymmetric Desymmetrization of Cyclohexadienones via Van Leusen Pyrrole Synthesis

MA Abozeid, HY Kim, K Oh - Organic Letters, 2022 - ACS Publications
A catalytic asymmetric desymmetrization of cyclohexadienones was accomplished via Van
Leusen pyrrole synthesis in the presence of a chiral silver catalyst. The ready access to …

Catalytic atroposelective dynamic kinetic resolution of biaryl lactones with activated isocyanides

L Qian, LF Tao, WT Wang, E Jameel, ZH Luo… - Organic …, 2021 - ACS Publications
We report herein an unprecedented atroposelective dynamic kinetic resolution of
Bringmann's lactones with C-nucleophiles. By the use of activated isocyanides as the …

Modular Synthesis of Tetrasubstituted Pyrroles via an Annulative Migration Reaction of Allenyl Ketones and p-Toluenesulfonylmethyl Isocyanide

R Xie, R Li, Q Zhao, Y Zhao, J Yao… - The Journal of Organic …, 2023 - ACS Publications
The metal-free cyclization of allenyl ketones and p-toluenesulfonylmethyl isocyanide
(TosMIC), promoted by Cs2CO3, provides a convenient access to tetrasubstituted pyrroles in …

Green and rapid and instrumental one-pot method for the synthesis of imidazolines having potential anti-SARS-CoV-2 main protease activity

S Azimi, MS Merza, F Ghasemi, HA Dhahi… - Sustainable Chemistry …, 2023 - Elsevier
Abstract The Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) is
responsible for ongoing epidemics in humans and some other mammals and has been …

Discovery of New Ligand with Quinoline Scaffold as Potent Allosteric Inhibitor of HIV‐1 and Its Copper Complexes as a Powerful Catalyst for the Synthesis of Chiral …

SG Azimi, G Bagherzade, MR Saberi… - Bioinorganic …, 2023 - Wiley Online Library
In this paper, the novel Schiff base ligand containing quinoline moiety and its novel copper
chelate complexes were successfully prepared. The catalytic activity of the final complex in …

Transition-metal-free three-component reaction: additive controlled synthesis of sulfonylated imidazoles

W Liu, Y Zhang, J He, Y Yu, J Yuan, X Ye… - The Journal of …, 2019 - ACS Publications
Two efficient transition-metal-free highly regioselective pathways for constructing
sulfonylated imidazoles via three-component reactions of amidines, ynals, and sodium …

Phosphine‐Catalyzed [3+2] Annulation of N‐2,2,2‐Trifluoroethylisatin Ketimines with γ‐Substituted Allenoates: Synthesis of Spiro[indoline‐3,2′‐pyrrole]

XY Wu, YN Gao, M Shi - European Journal of Organic …, 2019 - Wiley Online Library
Synthesis of spiro [indoline‐3, 2′‐pyrrole] scaffold compounds from N‐2, 2, 2‐
trifluoroethylisatin ketimines and γ‐substituted allenoates through a phosphine‐catalyzed …