Role of the CXCR6/CXCL16 axis in autoimmune diseases
N Bao, B Fu, X Zhong, S Jia, Z Ren, H Wang… - International …, 2023 - Elsevier
Abstract The C–X–C motif ligand 16, or CXCL16, is a chemokine that belongs to the ELR−
CXC subfamily. Its function is to bind to the chemokine receptor CXCR6, which is a G protein …
CXC subfamily. Its function is to bind to the chemokine receptor CXCR6, which is a G protein …
Neutrophil‐Mimetic, ROS Responsive, and Oxygen Generating Nanovesicles for Targeted Interventions of Refractory Rheumatoid Arthritis
Z Tang, S Meng, X Yang, Y Xiao, W Wang, Y Liu, K Wu… - Small, 2024 - Wiley Online Library
Rheumatoid arthritis (RA) is the most prevalent inflammatory joint disease worldwide,
leading to irreversible disability and even mortality. Unfortunately, current treatment …
leading to irreversible disability and even mortality. Unfortunately, current treatment …
Chemokines and lymphocyte homing in Sjögren's syndrome
J Liao, X Yu, Z Huang, Q He, J Yang, Y Zhang… - Frontiers in …, 2024 - frontiersin.org
Sjögren's syndrome (SS) is a chronic systemic autoimmune disease that typically presents
with lymphocyte, dendritic cell, and macrophage infiltration of exocrine gland ducts and the …
with lymphocyte, dendritic cell, and macrophage infiltration of exocrine gland ducts and the …
The glycosaminoglycan-binding chemokine fragment CXCL9 (74–103) reduces inflammation and tissue damage in mouse models of coronavirus infection
VLS Oliveira, CM Queiroz-Junior… - Frontiers in …, 2024 - frontiersin.org
Introduction Pulmonary diseases represent a significant burden to patients and the
healthcare system and are one of the leading causes of mortality worldwide. Particularly, the …
healthcare system and are one of the leading causes of mortality worldwide. Particularly, the …
Interleukin 27, like interferons, activates JAK-STAT signaling and promotes pro-inflammatory and antiviral states that interfere with dengue and chikungunya viruses …
JF Valdés-López, LJ Hernández-Sarmiento… - Frontiers in …, 2024 - frontiersin.org
Interferons (IFNs) are a family of cytokines that activate the JAK-STAT signaling pathway to
induce an antiviral state in cells. Interleukin 27 (IL-27) is a member of the IL-6 and/or IL-12 …
induce an antiviral state in cells. Interleukin 27 (IL-27) is a member of the IL-6 and/or IL-12 …
CXCL13 promotes TNF-α synthesis in rheumatoid arthritis through activating ERK/p38 pathway and inhibiting miR-330-3p generation
Rheumatoid arthritis (RA) is a well-known autoimmune disorder associated with joint pain,
joint swelling, cartilage and bone degradation as well as deformity. The chemokine (CXC …
joint swelling, cartilage and bone degradation as well as deformity. The chemokine (CXC …
Elaboration a ROS-responsive darutigenol prodrug nanoassemblies for inflammatory arthritis treatment
H Yan, D Wang, C Tian, L Zhao, Y Wang, G Long… - Nano Today, 2024 - Elsevier
Darutigenol (DL) is an active diterpenoid extracted from the traditional Chinese medicine
Sigesbeckia glabrescens (Makino) Makino, widely employed in the treatment of rheumatoid …
Sigesbeckia glabrescens (Makino) Makino, widely employed in the treatment of rheumatoid …
Progression of radio-labeled molecular imaging probes targeting chemokine receptors
H Yi, L Qin, X Ye, J Song, J Ji, T Ye, J Li, L Li - Critical Reviews in Oncology …, 2024 - Elsevier
Chemokine receptors are significantly expressed in the surface of most inflammatory cells
and tumor cells. Guided by chemokines, inflammatory cells which express the relevant …
and tumor cells. Guided by chemokines, inflammatory cells which express the relevant …
The Role of Autophagy as a Trigger of Post-Translational Modifications of Proteins and Extracellular Vesicles in the Pathogenesis of Rheumatoid Arthritis
G Riitano, S Recalchi, A Capozzi, V Manganelli… - International Journal of …, 2023 - mdpi.com
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease, characterized by
persistent joint inflammation, leading to cartilage and bone destruction. Autoantibody …
persistent joint inflammation, leading to cartilage and bone destruction. Autoantibody …
SRGN promotes macrophage recruitment through CCL3 in osteoarthritis
Y Zhang, Z Li, C Chen, W Wei, Z Li, H Zhou… - Connective Tissue …, 2024 - Taylor & Francis
Background Osteoarthritis (OA) is a degenerative disease that affects synovial joints and
leads to significant pain and disability, particularly in older adults. Infiltration of macrophages …
leads to significant pain and disability, particularly in older adults. Infiltration of macrophages …