Intracellular pathogens have evolved various efficient molecular armaments to subvert
innate defenses. Cellular ubiquitination, a normal physiological process to maintain …

Simple Summary Due to the broad functions of Toll-like receptor 2 (TLR2) in innate
immunity, the drive for the development of TLR2-targeted therapeutic treatments has …

Tuberculosis is a stern, difficult to treat chronic infection caused by acid-fast bacilli that tend
to take a long time to be eradicated from the host's environment. It requires the action of both …

Introduction Neutrophil granulocytes predominate in the lungs of patients infected with
Mycobacterium tuberculosis (Mtb) in earlier stages of the disease. During infection …

Tuberculosis (TB), which is caused by Mycobacterium tuberculosis (Mtb), is one of the most
lethal infectious disease worldwide, and it greatly affects human health. Some diagnostic …

Autophagy is an ubiquitous homeostatic pathway in mammalian cells and plays a significant
role in host immunity. Substantial evidence indicates that the ability of Mycobacterium …

Tuberculosis remains a common and dangerous chronic bacterial infection worldwide. It is
long-established that pathogenesis of many autoimmune diseases is mainly promoted by …

PE/PPE proteins of Mycobacterium tuberculosis (Mtb) target the host organelles to dictate
the outcome of infection. This study investigated the significance of PE6/Rv0335c protein's …

TNF, a pleiotropic proinflammatory cytokine, is important for protective immunity and
immunopathology during Mycobacterium tuberculosis (Mtb) infection, which causes …

Mycobacterium tuberculosis (Mtb) modulates diverse cell death pathways to escape the host
immune responses and favor its dissemination, a complex process of interest in …