γδT cells are an unconventional population of T lymphocytes that play an indispensable role
in host defense, immune surveillance, and homeostasis of the immune system. They display …

Summary Gut interleukin-17A (IL-17)-producing γδ T cells are tissue-resident cells that are
involved in both host defense and regulation of intestinal inflammation. However, factors that …

Gamma delta (γδ) T cells can effectively recognize and kill colorectal cancer (CRC) cells,
thereby suppressing tumor progression via multiple mechanisms. They also have abilities to …

Background Current therapeutics for ulcerative colitis (UC) have limitations. Classical
Formula Gegen Qinlian decoction (GQD) is derived from Shang Han Lun and has a long …

Abstract T-helper-17 (Th17) cells and related IL-17-producing (type17) lymphocytes are
abundant at the epithelial barrier. In response to bacterial and fungal infection, the signature …

Background Myeloid cells, especially mononuclear phagocytes, which include monocytes,
macrophages and dendritic cells (DC), play vital roles in innate immunity, and in the …

Objective Patients with spondyloarthritis (SpA) often present with microscopic signs of gut
inflammation, a risk factor for progressive disease. We investigated whether mucosal innate …

The finding that γδ T cells are present among tumor‐infiltrating lymphocytes in humans
suggests they participate in tumor immune surveillance, but their relevance is unclear …

Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, is
characterized by persistent inflammation in a hereditarily susceptible host. In addition to …

Ulcerative colitis (UC) is a chronic inflammatory disease of the intestine, whose
pathogenesis is not fully understood. Given that immune infiltration plays a key role in UC …