Strategies for optimizing DNA hybridization on surfaces
H Ravan, S Kashanian, N Sanadgol… - Analytical …, 2014 - Elsevier
Specific and predictable hybridization of the polynucleotide sequences to their
complementary counterparts plays a fundamental role in the rational design of new nucleic …
complementary counterparts plays a fundamental role in the rational design of new nucleic …
An experimentally-informed coarse-grained 3-site-per-nucleotide model of DNA: Structure, thermodynamics, and dynamics of hybridization
DM Hinckley, GS Freeman, JK Whitmer… - The Journal of chemical …, 2013 - pubs.aip.org
A new 3-Site-Per-Nucleotide coarse-grained model for DNA is presented. The model
includes anisotropic potentials between bases involved in base stacking and base pair …
includes anisotropic potentials between bases involved in base stacking and base pair …
DNA hybridization kinetics: zippering, internal displacement and sequence dependence
TE Ouldridge, P Šulc, F Romano, JPK Doye… - Nucleic acids …, 2013 - academic.oup.com
Although the thermodynamics of DNA hybridization is generally well established, the
kinetics of this classic transition is less well understood. Providing such understanding has …
kinetics of this classic transition is less well understood. Providing such understanding has …
Coarse-graining DNA for simulations of DNA nanotechnology
JPK Doye, TE Ouldridge, AA Louis… - Physical Chemistry …, 2013 - pubs.rsc.org
To simulate long time and length scale processes involving DNA it is necessary to use a
coarse-grained description. Here we provide an overview of different approaches to such …
coarse-grained description. Here we provide an overview of different approaches to such …
Ultrasensitive optical biosensor for detection of miRNA-155 using positively charged Au nanoparticles
F Hakimian, H Ghourchian, AS Hashemi, MR Arastoo… - Scientific reports, 2018 - nature.com
An ultrasensitive optical biosensor for microRNA-155 (miR-155) was developed to diagnose
breast cancer at early stages. At first, the probe DNA covalently bind to the negatively …
breast cancer at early stages. At first, the probe DNA covalently bind to the negatively …
Understanding the factors affecting the analytical performance of sandwich‐hybridization genosensors on gold electrodes
R Miranda‐Castro, N Santos‐Álvarez… - …, 2018 - Wiley Online Library
Hybridization‐based electrochemical DNA sensors have become a methodological
mainstay in a wide variety of fields. Among the possible assay formats, sandwich …
mainstay in a wide variety of fields. Among the possible assay formats, sandwich …
Coarse-grained modeling of DNA oligomer hybridization: length, sequence, and salt effects
DM Hinckley, JP Lequieu, JJ de Pablo - The Journal of chemical …, 2014 - pubs.aip.org
A recently published coarse-grained DNA model [DM Hinckley, GS Freeman, JK Whitmer,
and JJ de Pablo, J. Chem. Phys. 139, 144903 (2013)] is used to study the hybridization …
and JJ de Pablo, J. Chem. Phys. 139, 144903 (2013)] is used to study the hybridization …
The role of structural enthalpy in spherical nucleic acid hybridization
LK Fong, Z Wang, GC Schatz, E Luijten… - Spherical Nucleic …, 2020 - api.taylorfrancis.com
Spherical nucleic acids (SNAs) are a class of structures typically made nanoparticle by
arranging linear nucleic acids at high density around a small-molecule the development …
arranging linear nucleic acids at high density around a small-molecule the development …
DNA strand replacement mechanism in molecular beacons encoded for the detection of cancer biomarkers
M Stobiecka, A Chalupa - The Journal of Physical Chemistry B, 2016 - ACS Publications
Signaling properties of a fluorescent hairpin oligonucleotide molecular beacon (MB)
encoded to recognize protein survivin (Sur) mRNA have been investigated. The process of …
encoded to recognize protein survivin (Sur) mRNA have been investigated. The process of …
[图书][B] Coarse-grained modelling of DNA and DNA self-assembly
TE Ouldridge - 2012 - books.google.com
This thesis presents a novel coarse-grained model of DNA, in which bases are represented
as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena …
as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena …