Four enantiomeric 9-mer peptides named d-peptide A, B, C and D were designed and
synthesized on the basis of 43-mer insect defensins from two beetles. The d-9-mer peptides …

Human β-defensin 2 (hBD-2) is a 41-amino acid cationic peptide of the innate immune
system that serves as antimicrobial molecule. We determined the bactericidal activity of …

We successfully produced two human β-defensins (hBD-1 and hBD-2) in bacteria as
functional peptides and tested their antibacterial activities against Salmonella enterica …

Following the information obtained by a rational design study, a cyclic and helical-stabilized
analogue of the peptide Cm-p5 was synthetized. The cyclic monomer showed an increased …

Abstract The Japanese rhinoceros beetle Trypoxylus dichotomus is a giant beetle with
distinctive exaggerated horns present on the head and prothoracic regions of the male. T …

Biofilms are involved in the pathogenesis of 80% of microbial infections in humans [1]. This
prevalence is of major clinical importance as microbial populations growing in biofilms are …

Antimicrobial peptides are members of the immune system that protect the host from
infection. In this study, a potent and structurally novel antimicrobial peptide was isolated and …

Protaetiamycine is an insect defensin, a naturally occurring 43‐amino‐acid‐residue
antimicrobial peptide derived from the larvae of the beetle Protaetia brevitarsis. In a previous …

Synthetic d-and l-amino acid type cationic 9-mer peptides (all sequences were synthesized
as d-or l-amino acids) derived from the active sites of insect defensins were tested for their …

Beetles are the largest insect order and one of the most successful animal groups in terms of
number of species. The Japanese rhinoceros beetle Trypoxylus dichotomus (Coleoptera …