Antimicrobial peptides targeting gram-positive bacteria

N Malanovic, K Lohner - Pharmaceuticals, 2016 - mdpi.com
Antimicrobial peptides (AMPs) have remarkably different structures as well as biological
activity profiles, whereupon most of these peptides are supposed to kill bacteria via …

A review on antimicrobial peptides databases and the computational tools

S Ramazi, N Mohammadi, A Allahverdi, E Khalili… - Database, 2022 - academic.oup.com
Abstract Antimicrobial Peptides (AMPs) have been considered as potential alternatives for
infection therapeutics since antibiotic resistance has been raised as a global problem. The …

Antimicrobial peptides for therapeutic applications: a review

MD Seo, HS Won, JH Kim, T Mishig-Ochir, BJ Lee - Molecules, 2012 - mdpi.com
Antimicrobial peptides (AMPs) have been considered as potential therapeutic sources of
future antibiotics because of their broad-spectrum activities and different mechanisms of …

[HTML][HTML] Studies on anticancer activities of antimicrobial peptides

DW Hoskin, A Ramamoorthy - Biochimica et Biophysica Acta (BBA) …, 2008 - Elsevier
In spite of great advances in cancer therapy, there is considerable current interest in
developing anticancer agents with a new mode of action because of the development of …

Antimicrobial peptides: an overview of a promising class of therapeutics

A Giuliani, G Pirri, S Nicoletto - Open Life Sciences, 2007 - degruyter.com
Antibiotic resistance is increasing at a rate that far exceeds the pace of new development of
drugs. Antimicrobial peptides, both synthetic and from natural sources, have raised interest …

[HTML][HTML] Detergent-like actions of linear amphipathic cationic antimicrobial peptides

B Bechinger, K Lohner - Biochimica et Biophysica Acta (BBA) …, 2006 - Elsevier
Antimicrobial peptides have raised much interest as pathogens become resistant against
conventional antibiotics. We review biophysical studies that have been performed to better …

The role of hydrophobicity in the antimicrobial and hemolytic activities of polymethacrylate derivatives

K Kuroda, GA Caputo… - Chemistry–A European …, 2009 - Wiley Online Library
We synthesized cationic random amphiphilic copolymers by radical copolymerization of
methacrylate monomers with cationic or hydrophobic groups and evaluated their …

Antibacterial polymeric nanostructures for biomedical applications

J Chen, F Wang, Q Liu, J Du - Chemical communications, 2014 - pubs.rsc.org
The high incidence of bacterial infection and the growing resistance of bacteria to
conventional antibiotics have resulted in the strong need for the development of new …

[HTML][HTML] Structure, membrane orientation, mechanism, and function of pexiganan—a highly potent antimicrobial peptide designed from magainin

LM Gottler, A Ramamoorthy - Biochimica et Biophysica Acta (BBA) …, 2009 - Elsevier
The growing problem of bacterial resistance to conventional antibiotic compounds and the
need for new antibiotics have stimulated interest in the development of antimicrobial …

[HTML][HTML] Antimicrobial peptide mimics for improved therapeutic properties

S Rotem, A Mor - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2009 - Elsevier
The relatively recent recognition of the major role played by antimicrobial peptides (AMPs) in
sustaining an effective host response to immune challenges was greatly influenced by …