[HTML][HTML] The pancreatic stellate cell: a star on the rise in pancreatic diseases

MB Omary, A Lugea, AW Lowe… - The Journal of clinical …, 2007 - Am Soc Clin Investig
Pancreatic stellate cells (PaSCs) are myofibroblast-like cells found in the areas of the
pancreas that have exocrine function. PaSCs are regulated by autocrine and paracrine …

[HTML][HTML] Pancreatic stellate cell: Pandora's box for pancreatic disease biology

RR Bynigeri, A Jakkampudi, R Jangala… - World journal of …, 2017 - ncbi.nlm.nih.gov
Pancreatic stellate cells (PSCs) were identified in the early 1980s, but received much
attention after 1998 when the methods to isolate and culture them from murine and human …

Inflammation in acute and chronic pancreatitis

A Habtezion - Current opinion in gastroenterology, 2015 - journals.lww.com
Inflammation in acute and chronic pancreatitis : Current Opinion in Gastroenterology
Inflammation in acute and chronic pancreatitis : Current Opinion in Gastroenterology Log in or …

Role of macrophages during skeletal muscle regeneration and hypertrophy—Implications for immunomodulatory strategies

C Bernard, A Zavoriti, Q Pucelle… - Physiological …, 2022 - Wiley Online Library
Skeletal muscle is a plastic tissue that regenerates ad integrum after injury and adapts to
raise mechanical loading/contractile activity by increasing its mass and/or myofiber size, a …

Role of the immune system and the circadian rhythm in the pathogenesis of chronic pancreatitis: establishing a personalized signature for improving the effect of …

A Kessler, S Weksler-Zangen, Y Ilan - Pancreas, 2020 - journals.lww.com
Pancreatitis, in both acute and chronic forms, poses a major therapeutic challenge and is
associated with great morbidity and several complications. The nature of pancreatic injury in …

Berberine attenuates severity of chronic pancreatitis and fibrosis via AMPK-mediated inhibition of TGF-β1/Smad signaling and M2 polarization

S Bansod, N Doijad, C Godugu - Toxicology and Applied Pharmacology, 2020 - Elsevier
Berberine (BR) acts as an AMP-activated protein kinase (AMPK) activator which possesses
antioxidant and anti-inflammatory properties. In this study, we have investigated the effects …

[HTML][HTML] Necro-inflammatory response of pancreatic acinar cells in the pathogenesis of acute alcoholic pancreatitis

H Gu, J Werner, F Bergmann, DC Whitcomb… - Cell death & …, 2013 - nature.com
The role of pancreatic acinar cells in initiating necro-inflammatory responses during the
early onset of alcoholic acute pancreatitis (AP) has not been fully evaluated. We investigated …

COX-2 inhibitor reduces skeletal muscle hypertrophy in mice

ML Novak, W Billich, SM Smith… - American Journal …, 2009 - journals.physiology.org
Anti-inflammatory strategies are often used to reduce muscle pain and soreness that can
result from high-intensity muscular activity. However, studies indicate that components of the …

[HTML][HTML] Gut microbiota controls the development of chronic pancreatitis: A critical role of short-chain fatty acids-producing Gram-positive bacteria

LL Pan, ZN Ren, J Yang, BB Li, YW Huang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Chronic pancreatitis (CP) is a progressive and irreversible fibroinflammatory disorder,
accompanied by pancreatic exocrine insufficiency and dysregulated gut microbiota …

[HTML][HTML] Serotonin-RhoA/ROCK axis promotes acinar-to-ductal metaplasia in caerulein-induced chronic pancreatitis

X Tao, Q Chen, N Li, H Xiang, Y Pan, Y Qu… - Biomedicine & …, 2020 - Elsevier
The underlying molecular mechanisms of chronic pancreatitis (CP) developing into
pancreatic ductal adenocarcinoma (PDAC) remain largely unknown. Here we show that the …