Antifungal therapy: new advances in the understanding and treatment of mycosis

L Scorzoni, ACA de Paula e Silva, CM Marcos… - Frontiers in …, 2017 - frontiersin.org
The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …

Guideline: vulvovaginal candidosis (AWMF 015/072, level S2k)

A Farr, I Effendy, B Frey Tirri, H Hof, P Mayser… - Mycoses, 2021 - Wiley Online Library
Abstract Approximately 70‐75% of women will have vulvovaginal candidosis (VVC) at least
once in their lifetime. In premenopausal, pregnant, asymptomatic and healthy women and …

Candida Infections and Therapeutic Strategies: Mechanisms of Action for Traditional and Alternative Agents

GC de Oliveira Santos, CC Vasconcelos… - Frontiers in …, 2018 - frontiersin.org
The Candida genus comprises opportunistic fungi that can become pathogenic when the
immune system of the host fails. Candida albicans is the most important and prevalent …

Candida Infections, Causes, Targets, and Resistance Mechanisms: Traditional and Alternative Antifungal Agents

C Spampinato, D Leonardi - BioMed research international, 2013 - Wiley Online Library
The genus Candida includes about 200 different species, but only a few species are human
opportunistic pathogens and cause infections when the host becomes debilitated or …

Antifungal resistance and new strategies to control fungal infections

P Vandeputte, S Ferrari… - International journal of …, 2012 - Wiley Online Library
Despite improvement of antifungal therapies over the last 30 years, the phenomenon of
antifungal resistance is still of major concern in clinical practice. In the last 10 years the …

Non-albicans Candida spp. causing fungaemia: pathogenicity and antifungal resistance

V Krcmery, AJ Barnes - Journal of hospital infection, 2002 - Elsevier
Non-albicans Candida (NAC) species cause 35–65% of all candidaemias in the general
patient population. They occur more frequently in cancer patients, mainly in those with …

Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences

D Sanglard, FC Odds - The Lancet infectious diseases, 2002 - thelancet.com
Candida albicans and related species pathogenic for man become resistant to antifungal
agents, in particular triazole compounds, by expression of efflux pumps that reduce drug …

Rare and Emerging Opportunistic Fungal Pathogens: Concern for Resistance beyond Candida albicans and Aspergillus fumigatus

MA Pfaller, DJ Diekema - Journal of clinical microbiology, 2004 - Am Soc Microbiol
The frequency of invasive mycoses due to opportunistic fungal pathogens has increased
significantly over the past two decades (35, 74, 83, 88, 89, 101, 106). This increase in …

[图书][B] Porous media: applications in biological systems and biotechnology

K Vafai - 2010 - books.google.com
Presenting state-of-the-art research advancements, this volume explores innovative
approaches to effectively apply existing porous media technologies to biomedical …

Epidemiology and molecular mechanisms of antifungal resistance in Candida and Aspergillus

SS Gonçalves, ACR Souza, A Chowdhary, JF Meis… - Mycoses, 2016 - Wiley Online Library
The significant increase in the use of antifungal agents, both for the treatment of candidiasis
and invasive aspergillosis and as azole fungicides in agricultural crop protection has …