Molecular physiology of freeze tolerance in vertebrates

KB Storey, JM Storey - Physiological Reviews, 2017 - journals.physiology.org
Freeze tolerance is an amazing winter survival strategy used by various amphibians and
reptiles living in seasonally cold environments. These animals may spend weeks or months …

What we can learn from a tadpole about ciliopathies and airway diseases: Using systems biology in Xenopus to study cilia and mucociliary epithelia

P Walentek, IK Quigley - genesis, 2017 - Wiley Online Library
Over the past years, the Xenopus embryo has emerged as an incredibly useful model
organism for studying the formation and function of cilia and ciliated epithelia in vivo. This …

Xenbase: a genomic, epigenomic and transcriptomic model organism database

K Karimi, JD Fortriede, VS Lotay, KA Burns… - Nucleic acids …, 2018 - academic.oup.com
Abstract Xenbase (www. xenbase. org) is an online resource for researchers utilizing
Xenopus laevis and Xenopus tropicalis, and for biomedical scientists seeking access to data …

The Cell Ontology 2016: enhanced content, modularization, and ontology interoperability

AD Diehl, TF Meehan, YM Bradford, MH Brush… - Journal of biomedical …, 2016 - Springer
Abstract Background The Cell Ontology (CL) is an OBO Foundry candidate ontology
covering the domain of canonical, natural biological cell types. Since its inception in 2005 …

A rapid rate of sex-chromosome turnover and non-random transitions in true frogs

DL Jeffries, G Lavanchy, R Sermier, MJ Sredl… - Nature …, 2018 - nature.com
The canonical model of sex-chromosome evolution predicts that, as recombination is
suppressed along sex chromosomes, gametologs will progressively differentiate, eventually …

ATtRACT—a database of RNA-binding proteins and associated motifs

G Giudice, F Sánchez-Cabo, C Torroja… - Database, 2016 - academic.oup.com
RNA-binding proteins (RBPs) play a crucial role in key cellular processes, including RNA
transport, splicing, polyadenylation and stability. Understanding the interaction between …

Measuring absolute RNA copy numbers at high temporal resolution reveals transcriptome kinetics in development

NDL Owens, IL Blitz, MA Lane, I Patrushev, JD Overton… - Cell reports, 2016 - cell.com
Transcript regulation is essential for cell function, and misregulation can lead to disease.
Despite technologies to survey the transcriptome, we lack a comprehensive understanding …

The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery

M Toriyama, C Lee, SP Taylor, I Duran, DH Cohn… - Nature …, 2016 - nature.com
Cilia use microtubule-based intraflagellar transport (IFT) to organize intercellular signaling.
Ciliopathies are a spectrum of human diseases resulting from defects in cilia structure or …

Comparative transcriptomics suggest unique molecular adaptations within tardigrade lineages

M Kamilari, A Jørgensen, M Schiøtt, N Møbjerg - BMC genomics, 2019 - Springer
Background Tardigrades are renowned for their ability to enter cryptobiosis (latent life) and
endure extreme stress, including desiccation and freezing. Increased focus is on revealing …

Cryopreservation and laser nanowarming of zebrafish embryos followed by hatching and spawning

K Khosla, J Kangas, Y Liu, L Zhan, J Daly… - Advanced …, 2020 - Wiley Online Library
This study shows for the first time the ability to rewarm cryopreserved zebrafish embryos that
grow into adult fish capable of breeding normally. The protocol employs a single injection of …