Diabetes as one of the long-term COVID-19 complications: from the potential reason of more diabetic patients' susceptibility to COVID-19 to the possible caution of …

Y Sharbatdar, R Mousavian… - …, 2023 - Springer
According to recent researches, people with diabetes mellitus (type 1 and 2) have a higher
incidence of coronavirus disease 2019 (COVID-19), which is caused by a SARS-CoV-2 …

Single-nucleotide polymorphisms as important risk factors of diabetes among Middle East population

I Akhlaghipour, AR Bina, MR Mogharrabi, A Fanoodi… - Human Genomics, 2022 - Springer
Diabetes is a chronic metabolic disorder that leads to the dysfunction of various tissues and
organs, including eyes, kidneys, and cardiovascular system. According to the World Health …

[HTML][HTML] IL-6, TNF-α, and IL-10 levels/polymorphisms and their association with type 2 diabetes mellitus and obesity in Brazilian individuals

KF Rodrigues, NT Pietrani, AA Bosco… - … of endocrinology and …, 2017 - SciELO Brasil
Objective This study aimed to investigate the association of plasma TNF-α, IL-6, and lL-10
levels and cytokine gene polymorphisms [TNF-α (-308 G→ A), IL-6 (-174 C→ G) and IL-10 …

Glucose-Related Traits and Risk of Migraine—A Potential Mechanism and Treatment Consideration

MR Islam, DR Nyholt - Genes, 2022 - mdpi.com
Migraine and glucose-related (glycaemic) traits (fasting glucose, fasting insulin, and type 2
diabetes) are common and complex comorbid disorders that cause major economic and …

A review of type 2 diabetes mellitus predisposing genes

TO Yahaya, TF Salisu - Current diabetes reviews, 2020 - ingentaconnect.com
Introduction: Scientists are considering the possibility of treating diabetes mellitus (DM)
using a personalized approach in which various forms of the diseases will be treated based …

Infliximab ameliorates tumor necrosis factor‐alpha‐induced insulin resistance by attenuating PTP 1B activation in 3T3L1 adipocytes in vitro

LA Méndez‐García, F Trejo‐Millán… - Scandinavian …, 2018 - Wiley Online Library
Insulin resistance is the inability to respond to insulin and is considered a key
pathophysiological factor in the development of type 2 diabetes. Tumor necrosis factor …

[PDF][PDF] Investigation into the association between NLRP3 gene polymorphisms and susceptibility to type 2 diabetes mellitus

S Wang, F Fang, WB Jin, X Wang, XS Zheng - Genet Mol Res, 2015 - funpecrp.com.br
We conducted a case-control study to investigate the role of three common polymorphisms
(rs10754558, rs7512998, and rs12137901) of the gene NLR family, pyrin domain containing …

[HTML][HTML] Estimating the role of single-nucleotide polymorphism (rs1800629)-308 G/A of TNF-alpha gene as genetic marker associated with angina pectoris in a sample …

SY Abdulfattah, FT Samawi - Journal of Genetic Engineering and …, 2023 - Elsevier
Background Angina pectoris (AP) occurs when oxygen and other nutrients are insufficient to
meet the metabolic needs of the heart muscle. Stable angina is the most common, while the …

Comparative analysis of TNF-α (-308) gene polymorphism in Turkish patients with type 2 diabetes developing nephropathy and/or neuropathy

VG Can, OC Gunay, S Cesur - Scientific Reports, 2024 - nature.com
Abstract Type 2 diabetes (T2DM) is a group of chronic and systemic metabolic diseases.
Nephropathy (NP) and neuropathy (NR) are two common complications that severely affect …

Association of TNF-α 308G/A and LEPR Gln223Arg Polymorphisms with the Risk of Type 2 Diabetes Mellitus

M Trapali, D Houhoula, A Batrinou, A Kanellou, IF Strati… - Genes, 2021 - mdpi.com
The objective of the present study was to identify the association of the TNF-α-308G/A and
leptin receptor (LEPR) Gln223Arg polymorphisms with the risk of development of type 2 …