[HTML][HTML] Platelets in chronic obstructive pulmonary disease: an update on pathophysiology and implications for antiplatelet therapy

H Mallah, S Ball, J Sekhon, K Parmar, K Nugent - Respiratory medicine, 2020 - Elsevier
Platelets are essential mediators of inflammation and thrombosis. Chronic obstructive
pulmonary disease (COPD) is a heterogeneous multisystem disease, causing significant …

[HTML][HTML] Chronic lung diseases: prospects for regeneration and repair

PJ Barnes, GP Anderson, M Fagerås… - European Respiratory …, 2021 - Eur Respiratory Soc
COPD and idiopathic pulmonary fibrosis (IPF) together represent a considerable unmet
medical need, and advances in their treatment lag well behind those of other chronic …

The combination of hemogram indexes to predict exacerbation in stable chronic obstructive pulmonary disease

X Liu, H Ge, X Feng, J Hang, F Zhang, X Jin… - Frontiers in …, 2020 - frontiersin.org
Background: Chronic obstructive pulmonary disease (COPD) is characterized by pulmonary
and systemic inflammatory processes, and exacerbation of COPD represents a critical …

Association between routine blood biomarkers and clinical phenotypes and exacerbations in chronic obstructive pulmonary disease

A Nunez, V Marras, M Harlander, E Mekov… - … journal of chronic …, 2020 - Taylor & Francis
Introduction Chronic obstructive pulmonary disease (COPD) is associated with increased
lung and systemic inflammation. We aimed to identify associations between easy-to-obtain …

Platelet count and platelet indices in patients with stable and acute exacerbation of chronic obstructive pulmonary disease: a systematic review and meta-analysis

A Zinellu, P Paliogiannis, E Sotgiu… - COPD: Journal of …, 2021 - Taylor & Francis
Platelets play an important role in the pathophysiology of chronic obstructive pulmonary
disease (COPD) by mediating thrombotic, inflammatory, and immune processes in the lung …

Clinical phenotypes of atopy and asthma in COPD: a meta-analysis of SPIROMICS and COPDGene

N Putcha, A Fawzy, EC Matsui, MC Liu, RP Bowler… - Chest, 2020 - Elsevier
Background Little is known about the concordance of atopy with asthma COPD overlap.
Among individuals with COPD, a better understanding of the phenotypes characterized by …

Association of platelet count with all-cause mortality and risk of cardiovascular and respiratory morbidity in stable COPD

A Fawzy, JA Anderson, NJ Cowans, C Crim, R Wise… - Respiratory …, 2019 - Springer
Background Platelet count is a prognostic indicator in the general population and elderly.
Thrombocytosis during acute exacerbation of COPD (AECOPD) has been associated with …

[HTML][HTML] Urine and plasma markers of platelet activation and respiratory symptoms in COPD

A Fawzy, N Putcha, S Raju, H Woo, CT Lin… - … Diseases: Journal of …, 2023 - ncbi.nlm.nih.gov
Introduction: Antiplatelet therapy has been associated with fewer exacerbations and
reduced respiratory symptoms in chronic obstructive pulmonary disease (COPD). Whether …

Evolving concepts in chronic obstructive pulmonary disease blood-based biomarkers

M Cazzola, E Puxeddu, J Ora, P Rogliani - Molecular Diagnosis & …, 2019 - Springer
In recent years, there has been a great deal of interest in the identification and validation of
blood-based biomarkers for clinical use in chronic obstructive pulmonary disease (COPD) …

Thrombocytosis during stable state predicts mortality in bronchiectasis

S Aliberti, G Sotgiu, A Gramegna… - Annals of the …, 2021 - atsjournals.org
Rationale: Although platelets are considered key inflammatory mediators in respiratory
diseases, their role in bronchiectasis has not been fully explored. Objectives: We …