Mitochondria form dynamic networks in the cell that are balanced by the flux of iterative
fusion and fission events of the organelles. It is now appreciated that mitochondrial fission …

Mitochondria not only synthesize energy required for cellular functions but are also involved
in numerous cellular pathways including apoptosis, calcium homoeostasis, inflammation …

Mitochondria are highly dynamic organelles that constantly undergo fission and fusion.
Disruption of mitochondrial dynamics undermines their function and causes several human …

The quantification of membrane-associated biomolecular interactions is crucial to our
understanding of various cellular processes. State-of-the-art single-molecule approaches …

Lipid–protein interactions in cells are involved in various biological processes, including
metabolism, trafficking, signaling, host–pathogen interactions, and transmembrane …

We present an approach for preparing cryo-electron microscopy (cryo-EM) grids to study
short-lived molecular states. Using piezoelectric dispensing, two independent streams of …

In the last decade, molecular dynamics (MD) simulations have become an essential tool to
investigate the molecular properties of membrane trafficking processes, often in conjunction …

Dynamin mediates fission of vesicles from the plasma membrane during endocytosis.
Typically, dynamin is recruited from the cytosol to endocytic sites, requiring seconds to tens …

Caveolae are 70–100 nm diameter plasma membrane invaginations found in abundance in
adipocytes, endothelial cells, myocytes, and fibroblasts. Their bulb-shaped membrane …

Balanced fusion and fission are key for the proper function and physiology of mitochondria,.
Remodelling of the mitochondrial inner membrane is mediated by the dynamin-like protein …