The metabolic basis of Candida albicans morphogenesis and quorum sensing

TL Han, RD Cannon, SG Villas-Bôas - Fungal Genetics and Biology, 2011 - Elsevier
Candida albicans is a polymorphic fungus that has the ability to rapidly switch between
yeast and filamentous forms. The morphological transition appears to be a critical virulence …

Intracellular acetyl unit transport in fungal carbon metabolism

K Strijbis, B Distel - Eukaryotic cell, 2010 - Am Soc Microbiol
Acetyl coenzyme A (acetyl-CoA) is a central metabolite in carbon and energy metabolism.
Because of its amphiphilic nature and bulkiness, acetyl-CoA cannot readily traverse …

Drought re-routes soil microbial carbon metabolism towards emission of volatile metabolites in an artificial tropical rainforest

LK Honeker, G Pugliese, J Ingrisch, J Fudyma… - Nature …, 2023 - nature.com
Drought impacts on microbial activity can alter soil carbon fate and lead to the loss of stored
carbon to the atmosphere as CO2 and volatile organic compounds (VOCs). Here we …

Protein acetylation and acetyl coenzyme a metabolism in budding yeast

L Galdieri, T Zhang, D Rogerson, R Lleshi… - Eukaryotic …, 2014 - Am Soc Microbiol
Cells sense and appropriately respond to the physical conditions and availability of nutrients
in their environment. This sensing of the environment and consequent cellular responses …

Adaptation of Cryptococcus neoformans to mammalian hosts: integrated regulation of metabolism and virulence

J Kronstad, S Saikia, ED Nielson, M Kretschmer… - Eukaryotic …, 2012 - Am Soc Microbiol
The basidiomycete fungus Cryptococcus neoformans infects humans via inhalation of
desiccated yeast cells or spores from the environment. In the absence of effective immune …

ATP-citrate lyase is required for production of cytosolic acetyl coenzyme A and development in Aspergillus nidulans

MJ Hynes, SL Murray - Eukaryotic Cell, 2010 - Am Soc Microbiol
Acetyl coenzyme A (CoA) is a central metabolite in carbon and energy metabolism and in
the biosynthesis of cellular molecules. A source of cytoplasmic acetyl-CoA is essential for …

Proteomic analysis of cytoplasmic and surface proteins from yeast cells, hyphae, and biofilms of Candida albicans

M Martínez‐Gomariz, P Perumal, S Mekala… - …, 2009 - Wiley Online Library
Candida albicans is a human commensal and opportunistic pathogen that participates in
biofilm formation on host surfaces and on medical devices. We used DIGE analysis to …

The Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis

K Koselny, J Green, L DiDone… - Antimicrobial agents …, 2016 - Am Soc Microbiol
Only one new class of antifungal drugs has been introduced into clinical practice in the last
30 years, and thus the identification of small molecules with novel mechanisms of action is …

Manipulation of host diet to reduce gastrointestinal colonization by the opportunistic pathogen Candida albicans

KTW Gunsalus, SN Tornberg-Belanger, NR Matthan… - MSphere, 2016 - Am Soc Microbiol
Candida albicans, the most common human fungal pathogen, can cause systemic infections
with a mortality rate of~ 40%. Infections arise from colonization of the gastrointestinal (GI) …

Sequential mixed cultures: from syngas to malic acid

F Oswald, S Dörsam, N Veith, M Zwick… - Frontiers in …, 2016 - frontiersin.org
Synthesis gas (syngas) fermentation using acetogenic bacteria is an approach for
production of bulk chemicals like acetate, ethanol, butanol, or 2, 3-butandiol avoiding the …