[HTML][HTML] Kolaviron abates busulfan-induced episodic memory deficit and testicular dysfunction in rats: the implications for neuroendopathobiological changes during …

MO Oyovwi, B Ben-Azu, TP Edesiri, E Victor… - Biomedicine & …, 2021 - Elsevier
Busulfan is a popular antileukemia chemotherapeutic alkylating agent widely known to
induce variety of serious adverse effects including chemobrain-related cognitive …

[HTML][HTML] Antipsychotic effect of diosgenin in ketamine-induced murine model of schizophrenia: Involvement of oxidative stress and cholinergic transmission

B Ben-Azu, OG Adebayo, AR Fokoua… - IBRO Neuroscience …, 2024 - Elsevier
A decrease in the levels of antioxidant arsenals exacerbate generation of reactive
oxygen/nitrogen species, leading to neurochemical dysfunction, with significant impact on …

Effects of aerobic exercise and dietary flavonoids on cognition: a systematic review and meta-analysis

DK Joseph, AF Mat Ludin, FW Ibrahim… - Frontiers in …, 2023 - frontiersin.org
Introduction: Studies have shown that exercise increases angiogenesis and perfusion in the
hippocampus, activates neurogenesis in the dentate gyrus and increases synaptic plasticity …

Dyrk1a Phosphorylation of α‐Synuclein Mediating Apoptosis of Dopaminergic Neurons in Parkinson's Disease

Y Yong, Q Wu, X Meng, R Lu, H Xia, F Pei… - Parkinson's …, 2023 - Wiley Online Library
Objective. To investigate the role of aberrant Dyrk1a expression in phosphorylation
modification at the α‐synuclein serine 129 (Ser129) site to analyze its molecular mechanism …

Morus mesozygia leaf extract ameliorates behavioral deficits, oxidative stress and inflammation in Complete Freund's adjuvant-induced arthritis in rats

OO Ariyo, AM Ajayi, B Ben-Azu… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Morus mesozygia Stapf (Moraceae), otherwise
referred to as African mulberry, is utilized domestically as a remedy for a variety of …

Taurine, an essential amino acid, attenuates rotenone-induced Parkinson's disease in rats by inhibiting alpha-synuclein aggregation and augmenting dopamine …

JE Onuelu, B Ben-Azu, OG Adebayo, AR Fokoua… - Behavioural Brain …, 2024 - Elsevier
Reducing antioxidant levels exacerbates the generation of reactive oxygen/nitrogen
species, leading to alpha-synuclein aggregation and the degeneration of dopaminergic …

Mechanisms involved in the antidepressant-like action of orally administered 5-((4-methoxyphenyl) thio) benzo [c][1, 2, 5] thiadiazole (MTDZ) in male and female mice

K da Costa Rodrigues, M da Conceição Oliveira… - …, 2024 - Springer
Abstract Rationale The compound 5-((4-methoxyphenyl) thio) benzo [c][1, 2, 5] thiadiazole
(MTDZ) has recently been shown to inhibit in vitro acetylcholinesterase activity, reduce …

[HTML][HTML] Morin mitigate diethyl phthalate and bisphenol s–Induced hematotoxicity in rats model by abrogating oxidative stress

OE Eteng, CA Moses, CU Ogbonna, AO Adeleye… - Pharmacological …, 2022 - Elsevier
Endocrine disruptors affect biological systems, some as neglected home producing toxicity
(NHPT). We investigated the effect of morin on diethyl phthalate (DEP) and bisphenol S …

Morin improves learning and memory in healthy adult mice

H Martínez‐Coria, N Serrano‐García… - Brain and …, 2024 - Wiley Online Library
Background Morin is a flavonoid found in many edible fruits. The hippocampus and
entorhinal cortex play crucial roles in memory formation and consolidation. This study aimed …

[HTML][HTML] Adaptogenic action of diosgenin againsts chronic unpredictable mild stress-induced neuroimmune dysfunction of HPA axis reverses psychiatric behavior in …

B Ben-Azu, EO Chidebe, PEY Toloyai… - … Traditional Medicine and …, 2024 - Elsevier
Background Stressful life experiences are associated with neurobehavioral abnormalities,
such as anxiogenic-related depression and cognitive decline. Reportedly, adaptogens are …