Ceruloplasmin and other copper binding components of blood plasma and their functions: an update
MC Linder - Metallomics, 2016 - academic.oup.com
We know that blood plasma contains many proteins and also other components that bind
copper. The largest contributor to copper in the plasma is ceruloplasmin, which accounts for …
copper. The largest contributor to copper in the plasma is ceruloplasmin, which accounts for …
[HTML][HTML] Parkinson's disease: alterations in iron and redox biology as a key to unlock therapeutic strategies
A plethora of studies indicate that iron metabolism is dysregulated in Parkinson's disease
(PD). The literature reveals well-documented alterations consistent with established dogma …
(PD). The literature reveals well-documented alterations consistent with established dogma …
[HTML][HTML] Balancing acts: molecular control of mammalian iron metabolism
Iron is ubiquitous in the environment and in biology. The study of iron biology focuses on
physiology and homeostasis—understanding how cells and organisms regulate their iron …
physiology and homeostasis—understanding how cells and organisms regulate their iron …
The roles of iron in health and disease
PT Lieu, M Heiskala, PA Peterson, Y Yang - Molecular aspects of medicine, 2001 - Elsevier
Iron is vital for almost all living organisms by participating in a wide variety of metabolic
processes, including oxygen transport, DNA synthesis, and electron transport. However, iron …
processes, including oxygen transport, DNA synthesis, and electron transport. However, iron …
Chemistry and biology of eukaryotic iron metabolism
P Aisen, C Enns, M Wessling-Resnick - The international journal of …, 2001 - Elsevier
With rare exceptions, virtually all studied organisms from Archaea to man are dependent on
iron for survival. Despite the ubiquitous distribution and abundance of iron in the biosphere …
iron for survival. Despite the ubiquitous distribution and abundance of iron in the biosphere …
Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux
ZL Harris, AP Durley, TK Man… - Proceedings of the …, 1999 - National Acad Sciences
Aceruloplasminemia is an autosomal recessive disorder of iron metabolism. Affected
individuals evidence iron accumulation in tissue parenchyma in association with absent …
individuals evidence iron accumulation in tissue parenchyma in association with absent …
Iron metabolism
P Aisen, M Wessling-Resnick, EA Leibold - Current opinion in chemical …, 1999 - Elsevier
The understanding of iron metabolism at the molecular level has been enormously
expanded in recent years by new findings about the functioning of transferrin, the transferrin …
expanded in recent years by new findings about the functioning of transferrin, the transferrin …
Expression profiles of Arabidopsis thaliana in mineral deficiencies reveal novel transporters involved in metal homeostasis
H Wintz, T Fox, YY Wu, V Feng, W Chen… - Journal of Biological …, 2003 - ASBMB
Plants directly assimilate minerals from the environment and thus are key for acquisition of
metals by all subsequent consumers. Limited bio-availability of copper, zinc and iron in soil …
metals by all subsequent consumers. Limited bio-availability of copper, zinc and iron in soil …
Multi-copper oxidases and human iron metabolism
G Vashchenko, RTA MacGillivray - Nutrients, 2013 - mdpi.com
Multi-copper oxidases (MCOs) are a small group of enzymes that oxidize their substrate with
the concomitant reduction of dioxygen to two water molecules. Generally, multi-copper …
the concomitant reduction of dioxygen to two water molecules. Generally, multi-copper …
Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation
F Martin, T Linden, DM Katschinski, F Oehme, I Flamme… - Blood, 2005 - ashpublications.org
Cellular oxygen partial pressure is sensed by a family of prolyl-4-hydroxylase domain (PHD)
enzymes that modify hypoxia-inducible factor (HIF) α subunits. Upon hydroxylation under …
enzymes that modify hypoxia-inducible factor (HIF) α subunits. Upon hydroxylation under …