Chitosan derivatives and their application in biomedicine

W Wang, Q Meng, Q Li, J Liu, M Zhou, Z Jin… - International journal of …, 2020 - mdpi.com
Chitosan is a product of the deacetylation of chitin, which is widely found in nature. Chitosan
is insoluble in water and most organic solvents, which seriously limits both its application …

Therapeutic strategies to overcome cisplatin resistance in ovarian cancer

M Song, M Cui, K Liu - European journal of medicinal chemistry, 2022 - Elsevier
Ovarian cancer (OC) is one of the most common gynecologic tumors worldwide and one
with the highest mortality. Cisplatin (DDP) is the first platinum-based complex approved by …

[HTML][HTML] Polymeric drug delivery systems by additive manufacturing

S Borandeh, B van Bochove, A Teotia… - Advanced drug delivery …, 2021 - Elsevier
Additive manufacturing (AM) is gaining interests in drug delivery applications, offering
innovative opportunities for the design and development of systems with complex geometry …

The importance of animal models in biomedical research: current insights and applications

A Domínguez-Oliva, I Hernández-Ávalos… - Animals, 2023 - mdpi.com
Simple Summary The present review highlights and examines the importance of animal
models in relevant topics concerning current human and animal health. Over the past five …

Nanocarriers based novel and effective drug delivery system

S Khizar, N Alrushaid, FA Khan, N Zine… - International Journal of …, 2023 - Elsevier
Nanotechnology has ultimately come into the domain of drug delivery. Nanosystems for
delivery of drugs are promptly emerging science utilizing different nanoparticles as carriers …

Cisplatin in ovarian cancer treatment—known limitations in therapy force new solutions

A Zoń, I Bednarek - International journal of molecular sciences, 2023 - mdpi.com
Cisplatin is one of the most commonly used anticancer drugs worldwide. It is mainly used in
the treatment of ovarian cancer, but also used in testicular, bladder and lung cancers. The …

Strategies to obtain encapsulation and controlled release of small hydrophilic molecules

Q Li, X Li, C Zhao - Frontiers in bioengineering and biotechnology, 2020 - frontiersin.org
The therapeutic effect of small hydrophilic molecules is limited by the rapid clearance from
the systemic circulation or a local site of administration. The unsuitable pharmacokinetics …

Coating and functionalization strategies for nanogels and nanoparticles for selective drug delivery

F Pinelli, G Perale, F Rossi - Gels, 2020 - mdpi.com
Drug delivery is a fascinating research field with several development opportunities. Great
attention is now focused on colloidal systems, nanoparticles, and nanogels and on the …

Biomaterials for drug delivery and human applications

P Trucillo - Materials, 2024 - mdpi.com
Biomaterials embody a groundbreaking paradigm shift in the field of drug delivery and
human applications. Their versatility and adaptability have not only enriched therapeutic …

Sustained release of levobupivacaine from temperature-sensitive injectable hydrogel for long-term local anesthesia in postoperative pain management

YJ Zhang, K Shi, X Yang, W Chen, TH Wang, Y Kang… - Biomaterials, 2023 - Elsevier
Postoperative pain is a major concern for most of the surgical patients, and an inadequate
postoperative pain control may cause a series of complications. With an effective pain …