Comorbidities, multimorbidity and COVID-19

CD Russell, NI Lone, JK Baillie - Nature medicine, 2023 - nature.com
The influence of comorbidities on COVID-19 outcomes has been recognized since the
earliest days of the pandemic. But establishing causality and determining underlying …

Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus

B Raman, DA Bluemke, TF Lüscher… - European heart …, 2022 - academic.oup.com
Emerging as a new epidemic, long COVID or post-acute sequelae of coronavirus disease
2019 (COVID-19), a condition characterized by the persistence of COVID-19 symptoms …

[HTML][HTML] Neurological and psychiatric risk trajectories after SARS-CoV-2 infection: an analysis of 2-year retrospective cohort studies including 1 284 437 patients

M Taquet, R Sillett, L Zhu, J Mendel… - The Lancet …, 2022 - thelancet.com
Background COVID-19 is associated with increased risks of neurological and psychiatric
sequelae in the weeks and months thereafter. How long these risks remain, whether they …

[HTML][HTML] Persistent COVID-19 symptoms in a community study of 606,434 people in England

M Whitaker, J Elliott, M Chadeau-Hyam, S Riley… - Nature …, 2022 - nature.com
Long COVID remains a broadly defined syndrome, with estimates of prevalence and
duration varying widely. We use data from rounds 3–5 of the REACT-2 study (n= 508,707; …

Global prevalence of post-coronavirus disease 2019 (COVID-19) condition or long COVID: a meta-analysis and systematic review

C Chen, SR Haupert, L Zimmermann… - The Journal of …, 2022 - academic.oup.com
Background This study aims to examine the worldwide prevalence of post-coronavirus
disease 2019 (COVID-19) condition, through a systematic review and meta-analysis …

[HTML][HTML] Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

M Taquet, Z Skorniewska, A Hampshire… - Nature medicine, 2023 - nature.com
Post-COVID cognitive deficits, including 'brain fog', are clinically complex, with both objective
and subjective components. They are common and debilitating, and can affect the ability to …

Post-acute COVID-19 syndrome

D Montani, L Savale, N Noel… - European …, 2022 - Eur Respiratory Soc
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
responsible for the coronavirus disease 2019 (COVID-19) pandemic that has resulted in …

Associations of depression, anxiety, worry, perceived stress, and loneliness prior to infection with risk of post–COVID-19 conditions

S Wang, L Quan, JE Chavarro, N Slopen… - JAMA …, 2022 - jamanetwork.com
Importance Few risk factors for long-lasting (≥ 4 weeks) COVID-19 symptoms have been
identified. Objective To determine whether high levels of psychological distress before …

The IL-1β, IL-6, and TNF cytokine triad is associated with post-acute sequelae of COVID-19

C Schultheiß, E Willscher, L Paschold, C Gottschick… - Cell Reports …, 2022 - cell.com
Post-acute sequelae of COVID-19 (PASC) is emerging as global problem with unknown
molecular drivers. Using a digital epidemiology approach, we recruited 8,077 individuals to …

Gut microbiota in COVID-19: key microbial changes, potential mechanisms and clinical applications

F Zhang, RI Lau, Q Liu, Q Su, FKL Chan… - Nature Reviews …, 2023 - nature.com
The gastrointestinal tract is involved in coronavirus disease 2019 (COVID-19) caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gut microbiota has …