Diffuse large B-cell lymphoma

LH Sehn, G Salles - New England Journal of Medicine, 2021 - Mass Medical Soc
Diffuse Large B-Cell Lymphoma DLBCL, an aggressive cancer, accounts for about 30% of
all lymphomas. Empirical combination chemotherapy cures about 65% of patients initially …

2021 update on diffuse large B cell lymphoma: a review of current data and potential applications on risk stratification and management

S Susanibar‐Adaniya, SK Barta - American journal of …, 2021 - Wiley Online Library
Diffuse large B cell lymphoma (DLBCL), the most common type of Non‐Hodgkin lymphoma
(NHL), comprises a heterogeneous group of diseases with different biology, clinical …

[HTML][HTML] A probabilistic classification tool for genetic subtypes of diffuse large B cell lymphoma with therapeutic implications

GW Wright, JD Phelan, ZA Coulibaly, S Roulland… - Cancer cell, 2020 - cell.com
The development of precision medicine approaches for diffuse large B cell lymphoma
(DLBCL) is confounded by its pronounced genetic, phenotypic, and clinical heterogeneity …

Polatuzumab vedotin in relapsed or refractory diffuse large B-cell lymphoma

LH Sehn, AF Herrera, CR Flowers… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Patients with transplantation-ineligible relapsed/refractory (R/R) diffuse large B-
cell lymphoma (DLBCL) fare poorly, with limited treatment options. The antibody-drug …

Genomic profiling for clinical decision making in lymphoid neoplasms

L De Leval, AA Alizadeh, PL Bergsagel… - Blood, The Journal …, 2022 - ashpublications.org
With the introduction of large-scale molecular profiling methods and high-throughput
sequencing technologies, the genomic features of most lymphoid neoplasms have been …

Genetics and pathogenesis of diffuse large B-cell lymphoma

R Schmitz, GW Wright, DW Huang… - New England journal …, 2018 - Mass Medical Soc
Background Diffuse large B-cell lymphomas (DLBCLs) are phenotypically and genetically
heterogeneous. Gene-expression profiling has identified subgroups of DLBCL (activated B …

Diffuse large B‐cell lymphoma: 2019 update on diagnosis, risk stratification, and treatment

Y Liu, SK Barta - American journal of hematology, 2019 - Wiley Online Library
Abstract Disease Overview Diffuse large B‐cell lymphoma (DLBCL) is the most common
type of aggressive non‐Hodgkin lymphoma originating from the germinal center, and it …

[HTML][HTML] Rituximab in B-cell hematologic malignancies: a review of 20 years of clinical experience

G Salles, M Barrett, R Foà, J Maurer, S O'Brien… - Advances in …, 2017 - Springer
Rituximab is a human/murine, chimeric anti-CD20 monoclonal antibody with established
efficacy, and a favorable and well-defined safety profile in patients with various CD20 …

Double-hit gene expression signature defines a distinct subgroup of germinal center B-cell-like diffuse large B-cell lymphoma

D Ennishi, A Jiang, M Boyle, B Collinge… - Journal of Clinical …, 2019 - ascopubs.org
Purpose High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements
(HGBL-DH/TH) has a poor outcome after standard chemoimmunotherapy. We sought to …

The 2016 revision of the World Health Organization classification of lymphoid neoplasms

SH Swerdlow, E Campo, SA Pileri… - Blood, The Journal …, 2016 - ashpublications.org
A revision of the nearly 8-year-old World Health Organization classification of the lymphoid
neoplasms and the accompanying monograph is being published. It reflects a consensus …