Vitamin D 3 is made in the skin from 7-dehydrocholesterol under the influence of UV light.
Vitamin D 2 (ergocalciferol) is derived from the plant sterol ergosterol. Vitamin D is …

Before the twentieth century, it was not possible to describe the essentials of a diet that could
support life, growth and reproduction of higher animals. The discovery of vitamin A by …

Disturbances in mineral and bone metabolism are common in patients with CKD. A large
body of evidence indicates that these derangements are associated with increased mortality …

Paricalcitol versus calcitriol in the treatment of secondary hyperparathyroidism. Background
Management of secondary hyperparathyroidism has included the use of active vitamin D or …

Hyperparathyroidism occurs in most patients during the progression of chronic kidney
disease (CKD) and one of its initiating events, reduced serum levels of 1, 25 …

Abstract Paricalcitol (19-nor-1alpha-25-dihydroxyvitamin D2), a new vitamin D analog
developed for the treatment of secondary hyperparathyroidism, was evaluated in three …

Pathogenesis of vascular calcification in chronic kidney disease. Background
Hyperphosphatemia and hypercalcemia are independent risk factors for higher incidence of …

Background: Vitamin D deficiency is common in CKD and dialysis patients. Studies suggest
a physiologic autocrine and/or paracrine role for 1, 25 (OH) D produced via 1α-hydroxylase …

The vitamin D endocrine system plays a central role in mineral ion homeostasis through the
actions of the vitamin D hormone, 1, 25-dihydroxyvitamin D3 [1, 25 (OH) 2D3], on the …

Vitamin D derivatives and calcimimetics are used to treat secondary hyperparathyroidism in
patients with chronic renal failure. We investigated the effect of calcitriol, paricalcitol, and the …