Selective Termination of Autophagy-Dependent Cancers
A Roy, ML DePamphilis - Cells, 2024 - mdpi.com
The goal of cancer research is to identify characteristics of cancer cells that allow them to be
selectively eliminated without harming the host. One such characteristic is autophagy …
selectively eliminated without harming the host. One such characteristic is autophagy …
[HTML][HTML] A Systematic Overview of Single-Cell Transcriptomics Databases, their Use cases, and Limitations
Rapid advancements in high-throughput single-cell RNA-seq (scRNA-seq) technologies
and experimental protocols have led to the generation of vast amounts of genomic data that …
and experimental protocols have led to the generation of vast amounts of genomic data that …
Identification of RNA-binding protein hnRNP C targeting the 3'UTR of the TAP-associated glycoprotein tapasin in melanoma
Deregulation or loss of the human leukocyte antigen class I (HLA-I) molecules on tumor cells
leading to inhibition of CD8+ T cell recognition is an important tumor immune escape …
leading to inhibition of CD8+ T cell recognition is an important tumor immune escape …
[HTML][HTML] Integrated cancer cell-specific single-cell RNA-seq datasets of immune checkpoint blockade-treated patients
Immune checkpoint blockade (ICB) therapies have emerged as a promising avenue for the
treatment of various cancers. Despite their success, the efficacy of these treatments is …
treatment of various cancers. Despite their success, the efficacy of these treatments is …
[HTML][HTML] Targeting PIKfyve-driven lipid homeostasis as a metabolic vulnerability in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) subsists in a nutrient-deregulated
microenvironment, making it particularly susceptible to treatments that interfere with cancer …
microenvironment, making it particularly susceptible to treatments that interfere with cancer …