γ-aminobutyric acid (GABA) plays many of its key roles in embryonic development and
functioning of the central nervous system (CNS) by acting on ligand gated chloride …

The efficacy of sensory input to the spinal cord can be modulated presynaptically during
voluntary movement by mechanisms that depolarize afferent terminals and reduce …

Motoneurons receive thousands of excitatory and inhibitory synapses from descending
tracts and primary afferent fibers. The excitability of these neurons must be precisely …

In lower vertebrates, some cells contacting the central canal (CC) retain the ability to
proliferate, leading the reconstruction of the spinal cord after injury. A better understanding …

γ-Amino butyric acid (GABA) plays a key role in the regulation of central nervous system by
activating synaptic and extrasynaptic GABAA receptors. It is acknowledged that …

There is growing evidence that activation of high affinity extrasynaptic GABAA receptors in
the brain, cerebellum and spinal cord substantia gelatinosa results in a tonic inhibition …

The GABAergic agonist muscimol is used to inactivate brain regions in order to reveal
afferent inputs in isolation. However, muscimol's use in primary auditory cortex (A1) has …

Voltage-gated Ca2+ (CaV) channels are transmembrane proteins comprising three
subfamilies named CaV1, CaV2 and CaV3. The CaV3 channel subfamily groups the low …

Motoneurons are furnished with a vast repertoire of ionotropic and metabotropic receptors
as well as ion channels responsible for maintaining the resting membrane potential and …

Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the vertebrate
brain. GABA activates both ionotropic (GABAA) and metabotropic (GABAB) receptors in …