The rise in antibiotic-resistant bacteria, including strains that are resistant to last-resort
antibiotics, and the limited ability of antibiotics to eradicate biofilms have necessitated the …

Sepsis has been identified by the World Health Organization (WHO) as a global health
priority. There has been a tremendous effort to decipher underlying mechanisms …

Understanding microbial gene functions relies on the application of experimental genetics in
cultured microorganisms. However, the vast majority of bacteria and archaea remain …

The common and persistent failures to translate promising preclinical drug candidates into
clinical success highlight the limited effectiveness of disease models currently used in drug …

The increased resistance of pathogenic microorganisms is frequently attributed to the
extreme and inadequate use of antibiotics and transmission of resistance within and …

Infectious tropical diseases have a huge effect in terms of mortality and morbidity, and
impose a heavy economic burden on affected countries. These diseases predominantly …

Carbon dots (CDs) have a profound effect on elimination of bacteria, fungi, and viruses, but
the lack of an exact mechanism to interact with bacterial cells limits their development …

Fertilization is an important practical measure in agricultural production. As an important
nutrient element of plants, nitrogen (N) has a significant impact on the plant productivity and …

Commensal bacteria in the lower intestine of mammals are 10 times as numerous as the
body's cells. We investigated the relative importance of different immune mechanisms in …

Staphylococcus aureus causes invasive infections and easily acquires antibiotic resistance.
Even antibiotic-susceptible S. aureus can survive antibiotic therapy and persist, requiring …