Since the discovery of the first stable N-heterocyclic carbene (NHC) in the beginning of the
1990s, these divalent carbon species have become a common and available class of …

Methods for site-selective transformations of hydroxyl groups in carbohydrate derivatives are
reviewed. The construction of oligosaccharides of defined connectivity hinges on such …

A robust and practical protocol for preparing alkyl aryl ethers has been developed, which
relies on using two types of ligands to promote Cu-catalyzed alkoxylation of (hetero) aryl …

The tumor suppressor protein p53 is inactivated in the majority of human cancers and
remains a prime target for developing new drugs to reactivate its tumor suppressing activity …

The first example of oxidative C–H fluoroalkoxylation of quinoxalinones with fluoroalkyl
alcohols under transition-metal and solvent-free conditions is described. This approach …

Two catalyst systems are described, which together provide mild and general conditions for
the Pd-catalyzed C–O cross-coupling of primary alcohols. For activated substrates, such as …

Carbon‐heteroatom bond formation under transition‐metal free conditions provides a
powerful synthetic alternative for the efficient synthesis of valuable molecules. In particular …

This review article covers the recent developments in direct C–H functionalization of
quinoxalin-2 (1H)-one derivatives via radical additions at the C3 position. Reaction types …

Novel methodology for O‐functionalization of carbohydrate derivatives has been established
using bench‐stable and easily prepared iodonium (III) reagents. Both electron‐withdrawing …

We have developed a simple and direct method for the synthesis of aryl ethers by reacting
alcohols/phenols (ROH) with aryl ammonium salts (ArNMe3+), which are readily prepared …