Guanidine–curcumin complex-loaded amine-functionalised hollow mesoporous silica nanoparticles for breast cancer therapy

TM Viswanathan, K Chitradevi, A Zochedh… - Cancers, 2022 - mdpi.com
Simple Summary The combination of guanidine carbonate and curcumin-loaded hollow
mesoporous silica nanoparticles (GuC-HMSNAP) can be used as a therapeutic and to …

Galactomannan endowed biogenic silver nanoparticles exposed enhanced cancer cytotoxicity with excellent biocompatibility

H Padinjarathil, MM Joseph, BS Unnikrishnan… - International journal of …, 2018 - Elsevier
Galactomannan isolated from the fruit rind of Punica granatum was previously reported to
have excellent antioxidant, immunomodulatory and anticancer properties against both …

Emergence of gold‐mesoporous silica hybrid nanotheranostics: dox‐encoded, folate targeted chemotherapy with modulation of SERS fingerprinting for apoptosis …

AN Ramya, MM Joseph, S Maniganda, V Karunakaran… - Small, 2017 - Wiley Online Library
Strategically fabricated theranostic nanocarrier delivery system is an unmet need in
personalized medicine. Herein, this study reports a versatile folate receptor (FR) targeted …

Targeting groups employed in selective dendrons and dendrimers

R Vieira Gonzaga, S da Silva Santos, JV Da Silva… - Pharmaceutics, 2018 - mdpi.com
The design of compounds with directed action to a defined organ or tissue is a very
promising approach, since it can decrease considerably the toxicity of the drug/bioactive …

Indole-coumarin-thiadiazole hybrids: An appraisal of their MCF-7 cell growth inhibition, apoptotic, antimetastatic and computational Bcl-2 binding potential

PR Kamath, D Sunil, MM Joseph, AAA Salam… - European Journal of …, 2017 - Elsevier
Cancer therapeutic potential of thiadiazole hybrids incorporating pharmacologically active
indole and coumarin moieties have not been explored much. In the current investigation …

Biogenic cluster-encased gold nanorods as a targeted three-in-one theranostic nanoenvelope for SERS-guided photochemotherapy against metastatic melanoma

PT Sujai, MM Joseph, V Karunakaran… - ACS Applied Bio …, 2018 - ACS Publications
Effective treatment of malignant melanoma requires an appropriate combination of
therapeutic intervention with long-term prognosis as it often survives by monotherapies …

Exploration of biogenic nano-chemobiotics fabricated by silver nanoparticle and galactoxyloglucan with an efficient biodistribution in solid tumor investigated by SERS …

MM Joseph, JB Nair, RN Adukkadan… - … applied materials & …, 2017 - ACS Publications
An incredible exploration ensued of a dual modality nanocomposite wherein chemotherapy
in fusion with antibacterial efficacy is obtained in a biogenic fabrication, which transformed …

Chitosan-based theranostics for cancer therapy

AS Soubhagya, M Prabaharan - Chitosan for Biomaterials IV: Biomedical …, 2021 - Springer
Chitosan, a natural-based cationic polysaccharide, has a great potential to be utilized as
drug delivery systems, tissue engineering scaffolds, and wound dressings due to its …

New insight into a cancer theranostic probe: efficient cell-specific delivery of SN-38 guided by biotinylated poly (vinyl alcohol)

D Dutta, SM Alex, KN Bobba, KK Maiti… - ACS Applied Materials …, 2016 - ACS Publications
An optically modulated “turn-on” theranostic prodrug TP1 has been explored and formulated
with biotinylated poly (vinyl alcohol)(biotinPVA) to obtain desired pharmacokinetics. TP1 …

Peptide-conjugated PEGylated PAMAM as a highly affinitive nanocarrier towards HER2-overexpressing cancer cells

I Rostami, ZJ Zhao, ZH Wang, WK Zhang, Y Zhong… - RSC …, 2016 - pubs.rsc.org
Numerous effective polymers have been designed for drug and gene delivery; of these,
dendrimers have been a superior nanoplatform for targeted delivery to cancerous tumor …