Exploitation of plant growth promoting (PGP) rhizobacteria (PGPR) as crop inoculants could
propel sustainable intensification of agriculture to feed our rapidly growing population …

Much of contemporary synthetic biology research relies on the use of bacterial chassis for
plugging-in and plugging-out genetic circuits and new-to-nature functionalities. However …

A fundamental strategy of eukaryotic antiviral immunity involves the cGAS enzyme, which
synthesizes 2′, 3′-cGAMP and activates the effector STING. Diverse bacteria contain …

The intestinal microbiota influences mammalian host physiology in health and disease
locally in the gut but also in organs devoid of direct contact with bacteria such as the liver …

CRISPR–Cas technologies have enabled programmable gene editing in eukaryotes and
prokaryotes. However, the leading Cas9 and Cas12a enzymes are limited in their ability to …

Plasmids play an important role in bacterial genome evolution by transferring genes
between lineages. Fitness costs associated with plasmid carriage are expected to be a …

Bacterial outer membrane vesicle (OMV)-mediated delivery of proteins to host cells is an
important mechanism of host-pathogen communication. Emerging evidence suggests that …

Allelic exchange is an efficient method of bacterial genome engineering. This protocol
describes the use of this technique to make gene knockouts and knock-ins, as well as single …

Legumes obtain nitrogen from air through rhizobia residing in root nodules. Some species of
rhizobia can colonize cereals but do not fix nitrogen on them. Disabling native regulation …

Bacteria commonly live attached to surfaces in dense collectives containing billions of cells.
While it is known that motility allows these groups to expand en masse into new territory …