Bacillus megaterium—from simple soil bacterium to industrial protein production host

PS Vary, R Biedendieck, T Fuerch, F Meinhardt… - Applied microbiology …, 2007 - Springer
Bacillus megaterium has been industrially employed for more than 50 years, as it possesses
some very useful and unusual enzymes and a high capacity for the production of …

Prime time for Bacillus megaterium

PS Vary - Microbiology, 1994 - microbiologyresearch.org
Bacillw megaterium has fascinated microbiologists since it was first described over 100
years ago. It is interesting especiall!. because of its physiology, unusual and useful enzymes …

The sporulation transcription factor Spo0A is required for biofilm development in Bacillus subtilis

MA Hamon, BA Lazazzera - Molecular microbiology, 2001 - Wiley Online Library
Biofilms are structured communities of cells encased in a polymeric matrix and adherent to a
surface, interface or each other. We report here that the soil bacterium Bacillus subtilis forms …

Biochemical and genetic characterization of a competence pheromone from B. subtilis

R Magnuson, J Solomon, AD Grossman - Cell, 1994 - cell.com
We have purified and characterized a modified peptide pheromone that accumulates in
culture medium as B. subtilis grows to high density. This pheromone is required for the …

A site-directed Staphylococcus aureus hemB mutant is a small-colony variant which persists intracellularly

C von Eiff, C Heilmann, RA Proctor, C Woltz… - Journal of …, 1997 - Am Soc Microbiol
Although small-colony variants (SCVs) of Staphylococcus aureus have been recognized for
many years, this phenotype has only recently been related to persistent and recurrent …

Characterization of Tn917 insertion mutants of Staphylococcus epidermidis affected in biofilm formation

C Heilmann, C Gerke… - Infection and …, 1996 - Am Soc Microbiol
Biofilm formation is thought to result from the concerted action of primary attachment to a
specific surface and accumulation in multilayered cell clusters. Here we describe the …

spo0J is required for normal chromosome segregation as well as the initiation of sporulation in Bacillus subtilis

K Ireton, NW Gunther 4th, AD Grossman - Journal of bacteriology, 1994 - Am Soc Microbiol
The spo0J gene of Bacillus subtilis is required for the initiation of sporulation. We show that
the sporulation defect caused by null mutations in spo0J is suppressed by a null mutation in …

Gene replacement in Staphylococcus carnosus and Staphylococcus xylosus

R Brückner - FEMS microbiology letters, 1997 - academic.oup.com
A system for high-efficiency gene replacement in Staphylococcus carnosus and
Staphylococcus xylosus has been developed, that is based on temperature-sensitive …

Defining the genetic differences between wild and domestic strains of Bacillus subtilis that affect poly‐γ‐dl‐glutamic acid production and biofilm formation

NR Stanley, BA Lazazzera - Molecular microbiology, 2005 - Wiley Online Library
Biofilms are communities of microbial cells that are encased in a self‐produced, polymeric
matrix and are adherent to a surface. For several species of bacteria, an enhanced ability to …

Co-orientation of replication and transcription preserves genome integrity

A Srivatsan, A Tehranchi, DM MacAlpine… - PLoS genetics, 2010 - journals.plos.org
In many bacteria, there is a genome-wide bias towards co-orientation of replication and
transcription, with essential and/or highly-expressed genes further enriched co-directionally …