Fibrinogen conversion into insoluble fibrin and the formation of a stable clot is the final step
of the coagulation cascade. Fibrin clot porosity and its susceptibility to plasmin-mediated …

Fibrin is a major component of thrombi formed on the surface of atherosclerotic plaques.
Fibrin accumulation as a consequence of local blood coagulation activation takes place …

Abstract Background The glycoprotein VI (GPVI) signaling pathway was previously reported
to direct procoagulant platelet activity through collagen binding. However, the impact of …

Biomedical devices are prone to blood clot formation (thrombosis), and liquid‐infused
surfaces (LIS) are effective in reducing the thrombotic response. However, the mechanisms …

Significance: Aging is a complex process associated with an increased risk of many
diseases, including thrombosis. This review summarizes age-related prothrombotic …

Plasminogen is a protein involved in intravascular and extravascular fibrinolysis, as well as
in wound healing, cell migration, tissue formation and angiogenesis. In recent years its role …

Importance The use of warfarin to prevent thromboembolism in patients with infective
endocarditis (IE) remains controversial due to potentially increased bleeding risks. Design …

Blood clotting disorders consisting of unwanted blood clot formation or excessive bleeding
are some of the main causes of death worldwide. However, there are significant limitations …

The survival and proliferation of pathogenic Leptospira within a host are complex
phenomena that require careful consideration. The ErpY-like lipoprotein, found on the outer …

Cancer is associated with a high risk of venous thromboembolism (VTE) and its recurrence.
There is evidence that the prothrombotic fibrin clot phenotype, involving the formation of …