The population genetics of pathogenic Escherichia coli

E Denamur, O Clermont, S Bonacorsi… - Nature Reviews …, 2021 - nature.com
Escherichia coli is a commensal of the vertebrate gut that is increasingly involved in various
intestinal and extra-intestinal infections as an opportunistic pathogen. Numerous pathotypes …

Pathogenesis of gram-negative bacteremia

CL Holmes, MT Anderson, HLT Mobley… - Clinical microbiology …, 2021 - Am Soc Microbiol
Gram-negative bacteremia is a devastating public health threat, with high mortality in
vulnerable populations and significant costs to the global economy. Concerningly, rates of …

Species-and site-specific genome editing in complex bacterial communities

BE Rubin, S Diamond, BF Cress, A Crits-Christoph… - Nature …, 2022 - nature.com
Understanding microbial gene functions relies on the application of experimental genetics in
cultured microorganisms. However, the vast majority of bacteria and archaea remain …

ClermonTyping: an easy-to-use and accurate in silico method for Escherichia genus strain phylotyping

J Beghain, A Bridier-Nahmias… - Microbial …, 2018 - microbiologyresearch.org
The genus Escherichia is composed of Escherichia albertii, E. fergusonii, five cryptic
Escherichia clades and E. coli sensu stricto. Furthermore, the E. coli species can be divided …

The Clermont Escherichia coli phylo‐typing method revisited: improvement of specificity and detection of new phylo‐groups

O Clermont, JK Christenson… - Environmental …, 2013 - Wiley Online Library
There is extensive genetic substructure within the species E scherichia coli. In 2000 a simple
triplex PCR method was described by C lermont and colleagues that enables an E. coli …

Phylogenetic background and habitat drive the genetic diversification of Escherichia coli

M Touchon, A Perrin, JAM De Sousa, B Vangchhia… - PLoS …, 2020 - journals.plos.org
Escherichia coli is mostly a commensal of birds and mammals, including humans, where it
can act as an opportunistic pathogen. It is also found in water and sediments. We …

Characterization and rapid identification of phylogroup G in Escherichia coli, a lineage with high virulence and antibiotic resistance potential

O Clermont, OVA Dixit, B Vangchhia… - Environmental …, 2019 - Wiley Online Library
The phylogeny of the Escherichia coli species, with the identification of seven phylogroups
(A, B1, B2, C, D, E and F), is linked to the lifestyle of the strains. With the accumulation of …

CTX-M enzymes: origin and diffusion

R Cantón, JM González-Alba, JC Galán - Frontiers in microbiology, 2012 - frontiersin.org
CTX-M β-lactamases are considered a paradigm in the evolution of a resistance
mechanism. Incorporation of different chromosomal bla CTX-M related genes from different …

Pathogenicity Factors of Genomic Islands in Intestinal and Extraintestinal Escherichia coli

M Desvaux, G Dalmasso, R Beyrouthy… - Frontiers in …, 2020 - frontiersin.org
Escherichia coli is a versatile bacterial species that includes both harmless commensal
strains and pathogenic strains found in the gastrointestinal tract in humans and warm …

High Prevalence of Mucosa-Associated E. coli Producing Cyclomodulin and Genotoxin in Colon Cancer

E Buc, D Dubois, P Sauvanet, J Raisch, J Delmas… - PloS one, 2013 - journals.plos.org
Some Escherichia coli strains produce toxins designated cyclomodulins (CMs) which
interfere with the eukaryotic cell cycle of host cells, suggesting a possible link between these …