Infections at the maternal–fetal interface: an overview of pathogenesis and defence

CJ Megli, CB Coyne - Nature Reviews Microbiology, 2022 - nature.com
Infections are a major threat to human reproductive health, and infections in pregnancy can
cause prematurity or stillbirth, or can be vertically transmitted to the fetus leading to …

Malaria during pregnancy

M Fried, PE Duffy - Cold Spring Harbor …, 2017 - perspectivesinmedicine.cshlp.org
One hundred and twenty-five million women in malaria-endemic areas become pregnant
each year (see Dellicour et al. PLoS Med 7: e1000221 [2010]) and require protection from …

Malaria in pregnancy: pathogenesis and immunity

SJ Rogerson, L Hviid, PE Duffy, RFG Leke… - The Lancet infectious …, 2007 - thelancet.com
Understanding of the biological basis for susceptibility to malaria in pregnancy was recently
advanced by the discovery that erythrocytes infected with Plasmodium falciparum …

PfEMP1–a parasite protein family of key importance in Plasmodium falciparum malaria immunity and pathogenesis

L Hviid, ATR Jensen - Advances in parasitology, 2015 - Elsevier
Plasmodium falciparum causes the most severe form of malaria and is responsible for
essentially all malaria-related deaths. The accumulation in various tissues of erythrocytes …

Malaria in pregnancy: from placental infection to its abnormal development and damage

CLL Chua, SKM Khoo, JLE Ong… - Frontiers in …, 2021 - frontiersin.org
Malaria remains a global health burden with Plasmodium falciparum accounting for the
highest mortality and morbidity. Malaria in pregnancy can lead to the development of …

Poor birth outcomes in malaria in pregnancy: recent insights into mechanisms and prevention approaches

CLL Chua, W Hasang, SJ Rogerson, A Teo - Frontiers in immunology, 2021 - frontiersin.org
Pregnant women in malaria-endemic regions are susceptible to malaria in pregnancy, which
has adverse consequences on birth outcomes, including having small for gestational age …

Afucosylated Plasmodium falciparum-specific IgG is induced by infection but not by subunit vaccination

MD Larsen, M Lopez-Perez, EK Dickson… - Nature …, 2021 - nature.com
Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family members mediate
receptor-and tissue-specific sequestration of infected erythrocytes (IEs) in malaria. Antibody …

[HTML][HTML] Malaria in pregnancy

EN Takem, U D'Alessandro - Mediterranean journal of hematology …, 2013 - ncbi.nlm.nih.gov
Pregnant women have a higher risk of malaria compared to non-pregnant women. This
review provides an update on knowledge acquired since 2000 on P. falciparum and P. vivax …

Pathogenicity and virulence of malaria: Sticky problems and tricky solutions

IS Walker, SJ Rogerson - Virulence, 2023 - Taylor & Francis
Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths
each year, concentrated in Africa and in young children, but much of the world's population …

Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate

EE Vidal-Calvo, A Martin-Salazar, S Choudhary… - Nature …, 2024 - nature.com
Molecular similarities between embryonic and malignant cells can be exploited to target
tumors through specific signatures absent in healthy adult tissues. One such embryonic …