Lipid droplets in inflammation and cancer

PT Bozza, JPB Viola - … , Leukotrienes and Essential Fatty Acids (PLEFA), 2010 - Elsevier
Accumulation of lipid droplets (also known as lipid bodies or adiposomes) within leukocytes,
epithelial cells, hepatocytes and other non-adipocytic cells is a frequently observed …

Leukocyte lipid bodies—biogenesis and functions in inflammation

PT Bozza, KG Magalhães, PF Weller - … (BBA)-Molecular and Cell Biology of …, 2009 - Elsevier
Lipid body accumulation within leukocytes is a common feature in both clinical and
experimental infectious, neoplasic and other inflammatory conditions. Here, we will review …

Lipid body function in eicosanoid synthesis: an update

PT Bozza, I Bakker-Abreu, RA Navarro-Xavier… - … and essential fatty acids …, 2011 - Elsevier
Eicosanoids (prostaglandins, leukotrienes and lipoxins) are signaling lipids derived from
arachidonic acid metabolism that have important roles in physiological and pathological …

The role of prostaglandins in the initiation of parturition

DM Olson - Best practice & research Clinical obstetrics & …, 2003 - Elsevier
Parturition is composed of five separate but integrated physiological events: fetal membrane
rupture, cervical dilatation, myometrial contractility, placental separation and uterine …

Prostaglandin synthases: recent developments and a novel hypothesis

RJA Helliwell, LF Adams, MD Mitchell - Prostaglandins, Leukotrienes and …, 2004 - Elsevier
Cells are continuously exposed to cues, which signal cell survival or death. Fine-tuning of
these conflicting signals is essential for tissue development and homeostasis, and defective …

PGE2 vs PGF2α in human parturition

W Li, J Lu, C Zhang, W Wang, H Ying, L Myatt, K Sun - Placenta, 2021 - Elsevier
Abstract Prostaglandin E2 (PGE2) and F2α (PGF2α) are the two most prominent prostanoids
in parturition. They are involved in cervical ripening, membrane rupture, myometrial …

Metabolomics in premature labor: a novel approach to identify patients at risk for preterm delivery

R Romero, S Mazaki-Tovi, E Vaisbuch… - The journal of …, 2010 - Taylor & Francis
Objective. Biomarkers for preterm labor (PTL) and delivery can be discovered through the
analysis of the transcriptome (transcriptomics) and protein composition (proteomics) …

Prostaglandin E synthases: Understanding their pathophysiological roles through mouse genetic models

S Hara, D Kamei, Y Sasaki, A Tanemoto, Y Nakatani… - Biochimie, 2010 - Elsevier
Prostaglandin E synthase (PGES), which converts cyclooxygenase (COX)-derived
prostaglandin H2 (PGH2) to PGE2, is known to comprise a group of at least three structurally …

[PDF][PDF] Role of the prostaglandins in labour and prostaglandin receptor inhibitors in the prevention of preterm labour

DM Olson, C Ammann - Front Biosci, 2007 - researchgate.net
Introduction: The Preterm Birth Paradigm and the Roles of Prostaglandins in Labour 3.
Materials and Methods: Uterine Activation Genes and their Proteins 4. Results …

Prostaglandin E synthase: a novel drug target for inflammation and cancer

M Murakami, I Kudo - Current pharmaceutical design, 2006 - ingentaconnect.com
Prostaglandin E synthase (PGES), which converts cyclooxygenase (COX)-derived
prostaglandin (PG) H2 to PGE2, occurs in multiple forms with distinct enzymatic properties …