Inhalable nanoparticle-based dry powder formulations for respiratory diseases: challenges and strategies for translational research

HW Chan, S Chow, X Zhang, Y Zhao, HHY Tong… - AAPS …, 2023 - Springer
The emergence of novel respiratory infections (eg, COVID-19) and expeditious development
of nanoparticle-based COVID-19 vaccines have recently reignited considerable interest in …

[HTML][HTML] Pulmonary inhalation for disease treatment: Basic research and clinical translations

B Wang, L Wang, Q Yang, Y Zhang, T Qinglai, X Yang… - Materials Today Bio, 2024 - Elsevier
Pulmonary drug delivery has the advantages of being rapid, efficient, and well-targeted, with
few systemic side effects. In addition, it is non-invasive and has good patient compliance …

Preparation of chitin/MXene/poly (L-arginine) composite aerogel spheres for specific adsorption of bilirubin

M Yao, G Zhang, D Shao, S Ding, L Li, H Li… - International Journal of …, 2023 - Elsevier
Currently, hemoperfusion is clinically the most rapid and effective treatment for removing
toxins from the blood. The core of hemoperfusion is the sorbent inside the hemoperfusion …

Supplementation of thymoquinone nanoparticles to semen extender boosts cryotolerance and fertilizing ability of buffalo bull spermatozoa

WA Khalil, MAE Hassan, MA El-Harairy, SA Abdelnour - Animals, 2023 - mdpi.com
Simple Summary Semen cryopreservation is a reliable technique used in artificial
reproduction technology to preserve and transmit buffaloes' superior genetic qualities …

Biobased Semi-Crystalline Polyesteramides from 2, 5-Furandicarboxylic Acid and 5, 5′-Isopropylidene Bis (2-furfurylamine): Synthesis toward Crystallinity and …

K Rihab, A Bougarech, S Zaidi… - ACS Sustainable …, 2023 - ACS Publications
Polymers based on furans have received much attention in recent years due to their
renewable origin and high-performance properties; nevertheless, the important class of …

Taste Masking of Promethazine Hydrochloride Using l-Arginine Polyamide-Based Nanocapsules

HS Alyami, DK Ali, Q Jarrar, A Jaradat, H Aburass… - Molecules, 2023 - mdpi.com
Promethazine hydrochloride (PMZ), a potent H1-histamine blocker widely used to prevent
motion sickness, dizziness, nausea, and vomiting, has a bitter taste. In the present study …

Novel poly (ester amide) derived from tyrosine amino acid for targeted pulmonary drug delivery of fluticasone propionate

H AbdulKarim, DK Ali, E Taybeh… - Journal of Applied …, 2023 - Wiley Online Library
Nanoaggregates made from amino acid‐based polymers have been an important platform
for targeted drug delivery systems such as the lungs. Therefore, the aim of the present study …

Development and Characterization of Transdermal Patches Using Novel Thymoquinone-L-Arginine-Based Polyamide Nanocapsules for Potential Use in the …

EZ Dahmash, LM Attiany, D Ali, SM Assaf, J Alkrad… - AAPS …, 2024 - Springer
Thymoquinone (TQ) is a phytochemical compound present in Nigella sativa and has
potential benefits for treating dermatological conditions such as psoriasis. However, its …

[HTML][HTML] Quality by design for the synthesis and optimisation of arginine-poly (ester-amide) nanocapsules as promising carriers for nose-brain delivery of …

NM Al-Baldawi, DK Ali, Q Jarrar… - Journal of Drug Delivery …, 2023 - Elsevier
Polymeric nanocapsules for direct brain drug delivery through intranasal is a promising
route for drugs that need to reach the brain directly with rapid onset of action and high …

Preclinical evaluation of novel synthesised nanoparticles based on tyrosine poly (ester amide) for improved targeted pulmonary delivery

EZ Dahmash, NR Achkar, DK Ali, Q Jarrar, A Iyire… - Scientific Reports, 2024 - nature.com
Fixed dose combinations (FDCs) incorporating two or three medicines in a single inhaler
have been created to enhance patient compliance and hence clinical outcomes. However …