Patterns and evolutionary consequences of pleiotropy
J Zhang - Annual Review of Ecology, Evolution, and Systematics, 2023 - annualreviews.org
Pleiotropy refers to the phenomenon of one gene or one mutation affecting multiple
phenotypic traits. While the concept of pleiotropy is as old as Mendelian genetics, functional …
phenotypic traits. While the concept of pleiotropy is as old as Mendelian genetics, functional …
Divergence of duplicate genes in exon–intron structure
Gene duplication plays key roles in organismal evolution. Duplicate genes, if they survive,
tend to diverge in regulatory and coding regions. Divergences in coding regions, especially …
tend to diverge in regulatory and coding regions. Divergences in coding regions, especially …
The loci of repeated evolution: a catalog of genetic hotspots of phenotypic variation
A Martin, V Orgogozo - Evolution, 2013 - academic.oup.com
What is the nature of the genetic changes underlying phenotypic evolution? We have
catalogued 1008 alleles described in the literature that cause phenotypic differences among …
catalogued 1008 alleles described in the literature that cause phenotypic differences among …
Evolution of transcription networks—lessons from yeasts
H Li, AD Johnson - Current Biology, 2010 - cell.com
That regulatory evolution is important in generating phenotypic diversity was suggested
soon after the discovery of gene regulation. In the past few decades, studies in animals have …
soon after the discovery of gene regulation. In the past few decades, studies in animals have …
[图书][B] Mutation-driven evolution
M Nei - 2013 - books.google.com
The purpose of this book is to present a new mechanistic theory of mutation-driven evolution
based on recent advances in genomics and evolutionary developmental biology. The theory …
based on recent advances in genomics and evolutionary developmental biology. The theory …
Modes of gene duplication contribute differently to genetic novelty and redundancy, but show parallels across divergent angiosperms
Background Both single gene and whole genome duplications (WGD) have recurred in
angiosperm evolution. However, the evolutionary effects of different modes of gene …
angiosperm evolution. However, the evolutionary effects of different modes of gene …
Gene co-expression network connectivity is an important determinant of selective constraint
While several studies have investigated general properties of the genetic architecture of
natural variation in gene expression, few of these have considered natural, outbreeding …
natural variation in gene expression, few of these have considered natural, outbreeding …
[HTML][HTML] Widespread adaptive evolution during repeated evolutionary radiations in New World lupins
The evolutionary processes that drive rapid species diversification are poorly understood. In
particular, it is unclear whether Darwinian adaptation or non-adaptive processes are the …
particular, it is unclear whether Darwinian adaptation or non-adaptive processes are the …
Population genetics, pleiotropy, and the preferential fixation of mutations during adaptive evolution
MA Streisfeld, MD Rausher - Evolution, 2011 - academic.oup.com
Ongoing debate centers on whether certain types of mutations are fixed preferentially during
adaptive evolution. Although there has been much discussion, no quantitative framework …
adaptive evolution. Although there has been much discussion, no quantitative framework …
The evolution and adaptive potential of transcriptional variation in sticklebacks—signatures of selection and widespread heritability
Evidence implicating differential gene expression as a significant driver of evolutionary
novelty continues to accumulate, but our understanding of the underlying sources of …
novelty continues to accumulate, but our understanding of the underlying sources of …